Fumio Toda

Bio: Fumio Toda is an academic researcher from Ehime University. The author has contributed to research in topics: Inclusion compound & Enantioselective synthesis. The author has an hindex of 20, co-authored 99 publications receiving 1323 citations. Previous affiliations of Fumio Toda include Okayama University of Science & Okayama University.

Aldol condensations in the absence of solvent: acceleration of the reaction and enhancement of the stereoselectivity

Abstract: Some aldol condensation reactions proceeded more efficiently and stereoselectively in the absence of solvent than in solution. When the aldol reaction was carried in an inclusion complex with an optically active host compound, diastereo- and enantio-selective reaction occurred.

Reformatsky and Luche reaction in the absence of solvent

Abstract: Synthese d'hydroxyesters par la reaction de Reformatsky, et d'alcools homoallyliques par la reaction de Luche a partir des aldehydes ou des cetones correspondants

Efficient optical resolution of 2,2'-dihydroxy-1,1'-binaphthyl and related compounds by complex formation with novel chiral host compounds derived from tartaric acid

Abstract: Les composes hotes utilises sont des bis-dialkylamides d'acides dimethoxy-2,3 succiniques et le bis-dimethylamide de l'acide dimethyl-2,2 dioxolanne-1,3dicarboxylique-4,5

Solvent-free Dieckmann condensation reactions of diethyl adipate and pimelate

Abstract: Dieckmann condensation reactions of diethyl adipate and pimelate proceeded efficiently in the absence of solvent, and the reaction products were collected by a direct distillation from the solvent-free reaction mixture.

Mechanochemistry: opportunities for new and cleaner synthesis

Abstract: The aim of this critical review is to provide a broad but digestible overview of mechanochemical synthesis, i.e. reactions conducted by grinding solid reactants together with no or minimal solvent. Although mechanochemistry has historically been a sideline approach to synthesis it may soon move into the mainstream because it is increasingly apparent that it can be practical, and even advantageous, and because of the opportunities it provides for developing more sustainable methods. Concentrating on recent advances, this article covers industrial aspects, inorganic materials, organic synthesis, cocrystallisation, pharmaceutical aspects, metal complexes (including metal–organic frameworks), supramolecular aspects and characterization methods. The historical development, mechanistic aspects, limitations and opportunities are also discussed (314 references).

Asymmetric catalysis by chiral hydrogen-bond donors.

Abstract: Hydrogen bonding is responsible for the structure of much of the world around us. The unusual and complex properties of bulk water, the ability of proteins to fold into stable three-dimensional structures, the fidelity of DNA base pairing, and the binding of ligands to receptors are among the manifestations of this ubiquitous noncovalent interaction. In addition to its primacy as a structural determinant, hydrogen bonding plays a crucial functional role in catalysis. Hydrogen bonding to an electrophile serves to decrease the electron density of this species, activating it toward nucleophilic attack. This principle is employed frequently by Nature's catalysts, enzymes, for the acceleration of a wide range of chemical processes. Recently, organic chemists have begun to appreciate the tremendous potential offered by hydrogen bonding as a mechanism for electrophile activation in small-molecule, synthetic catalyst systems. In particular, chiral hydrogen-bond donors have emerged as a broadly applicable class of catalysts for enantioselective synthesis. This review documents these advances, emphasizing the structural and mechanistic features that contribute to high enantioselectivity in hydrogen-bond-mediated catalytic processes.

Alternative synthetic methods through new developments in catalysis by gold.

Abstract: 2.7. Hydroxylation Reactions of Allenes 3282 2.8. Hydroamination Reactions of Allenes 3284 2.9. Hydrothiolation of Allenes 3284 2.10. Hydroalxoxylation of Alkenes and 1,3-Dienes 3286 2.11. Hydroamination of Alkenes and 1,3-Dienes 3287 2.12. Hydrothiolation of Conjugated Olefins 3289 3. Activation of Carbonyl/Imine Groups and Alcohols 3289 3.1. Condensation Reactions 3289 3.2. Addition Reactions 3291 3.3. Aldol Reactions 3294 3.4. Hydroand Carbosilylation Reactions 3295 3.5. Nucleophilic Substitution Reactions of Alcohols 3297 4. Gold-Catalyzed C-H Bond Functionalization 3297 4.1. Csp3-H Bond Functionalization 3298 4.2. Csp2-H Bond Functionalization 3299 4.3. Csp-H Bond Functionalization 3304 5. Gold-Catalyzed Selective Reductions 3305 5.1. Catalytic Hydrogenation of Alkenes 3306 5.2. Selective Reductions of R, -Unsaturated Carbonyl Groups and 1,3-Dienes 3306

Solvent-free organic synthesis

Abstract: Solvent-free organic synthesis , Solvent-free organic synthesis , کتابخانه دیجیتال جندی شاپور اهواز