G. Fatti

TL;DR: The survival improvement observed until 2001 was due to an increasing number of tumours diagnosed in early stages and in a background of compensated cirrhosis, and a growing and better use of locoregional treatments, and national policies aimed at implementing surveillance programmes for at risk patients.

TL;DR: CAI achieves adequate sensitivity and NPV as a surveillance test for the early detection of HCC in cirrhosis as well as a validation group that considered 36 subsequent patients diagnosed with HCC, matched with contemporary cancer-free controls.

TL;DR: SCCA-IgM serum measurement could permit implementation of a two step surveillance: an initial serological surveillance, based on the annual monitoring of this biomarker, and the conventional surveillance by semiannual US when SCCA+ve cirrhotic patients at low HCC risk becomes >200 AU/mL.

TL;DR: In this paper , the authors evaluated the cost-effectiveness of glaucoma screening with imaging devices and telemedicine based on a screening campaign performed in Spain and concluded that the screening strategy implemented in their analysis was cost-effective compared with opportunistic case finding.