G. I. Nikishin

Bio: G. I. Nikishin is an academic researcher from Russian Academy of Sciences. The author has contributed to research in topics: Radical & Homolysis. The author has an hindex of 11, co-authored 280 publications receiving 540 citations.

Homolytic cyclization of 1,3-propanedithiol to 1,2-dithiolane in the presence of 2,5-dimethyl-2,4-hexadiene

Abstract: 2,2-Diethyl-1,3-propanedithiol undergoes cyclization to 4,4-diethyl-1,2-dithiolane upon interaction with 2,5-dimethyl-2,4-hexadiene in benzene in the presence of azodiisolbutyronitrile. The reaction proceeds according to the radical chain mechanism.

Homolytic reactions of dithiols with alkynes: A method of synthesis of 1,3- and 1,4-dithiacycloalkanes

Abstract: The homolytic addition of alkanedithiols to alkynes gives 5–7-membered 1,3- or 1,4-dithiacycloalkanes, depending on the structures of the components

Electrochemical oxidation of tetramethyl esters of α,α,ω,ω-alcaneteracarboxylic acids

Abstract: Cyclization of esters of butane-1,1,4,4- and pentane-1,1,5,5-tetracarboxylic acids during electrolysis in methanol in the presence of Nal produces, with a yield of 95%, the esters of cyclobutane-1,1,2,2- and cyclopentane-1,1,2,2-tetracarboxylic acids. Under similar conditions, esters of the highest α,α,ω,ω-alkanetetracarboxylic acids undergo iodation and hydroxymethylation due to electrical oxidation of methanol to formaldehyde. During electrolysis in methanol in the presence of NaOAc, the esters of α,α,ω,ω-alkanetetracarboxylic acids undergo effective hydroxymethylation, followed by cyclization into substituted five- and six-member lactones, or tetrahydrofurans when structurally possible.

Electrochemical and chemical oxidation of alcohols in a two-phase system using N-oxopiperidinium salt: Synthesis of 4-chlorobutanal, formylcyclopropanes, andm-phenoxybenzaldehyde

Abstract: Oxidation of 4-chlorobutanol-1, cyclopropylcarbinols, andm-phenoxybenzyl alcohol with electrogenerated bromine, molecular bromine, and sodium hypochlorite using N-oxopiperidinium salt in the two-phase system CH2Cl2—water gave the corresponding carbonyl compounds with good yields

Electrochemical oxidation of malonic esters in the presence of catalyst carriers — salts of hydriodic acid

Abstract: 1. The throughgoing electrochemical oxidation of esters of malonic acid in the presence of catalyst carriers — salts of hydriodic acid — in methanol and ethanol leads to esters of ethylenetetracarboxylic acid and the products of the addition to it of alcohols and dialkyl malonates, namely 1-alkoxyethane-1,1,2,2-tetracarboxylic and propane-1,1,2,2,3,3-hexacarboxylic esters. 2. The results of the reaction depends to a significant degree on the temperature and the nature of the cation in the catalyst carrier. Under optimal conditions, each of the enumerated esters can be obtained with the yield of 50–80%.

I and i

Abstract: There is, I think, something ethereal about i —the square root of minus one. I remember first hearing about it at school. It seemed an odd beast at that time—an intruder hovering on the edge of reality. Usually familiarity dulls this sense of the bizarre, but in the case of i it was the reverse: over the years the sense of its surreal nature intensified. It seemed that it was impossible to write mathematics that described the real world in …

Cobalt-Catalyzed C―H Activation

Abstract: Catalytic C–H activation has emerged as a powerful tool for sustainable syntheses. In the recent years, notable success was achieved with the development of cobalt-catalyzed C–H functionalizations with either in situ generated or single-component cobalt-complexes under mild reaction conditions. Herein, recent progress in the field of organometallic cobalt-catalyzed C–H activation is reviewed until November 2015.

Catalytic Enantioselective Transformations Involving C-H Bond Cleavage by Transition-Metal Complexes.

Abstract: The development of new methods for the direct functionalization of unactivated C–H bonds is ushering in a paradigm shift in the field of retrosynthetic analysis. In particular, the catalytic enantioselective functionalization of C–H bonds represents a highly atom- and step-economic approach toward the generation of structural complexity. However, as a result of their ubiquity and low reactivity, controlling both the chemo- and stereoselectivity of such processes constitutes a significant challenge. Herein we comprehensively review all asymmetric transition-metal-catalyzed methodologies that are believed to proceed via an inner-sphere-type mechanism, with an emphasis on the nature of stereochemistry generation. Our analysis serves to document the considerable and rapid progress within in the field, while also highlighting limitations of current methods.