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G. I. Nikishin

Bio: G. I. Nikishin is an academic researcher from Russian Academy of Sciences. The author has contributed to research in topics: Radical & Homolysis. The author has an hindex of 11, co-authored 280 publications receiving 540 citations.


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TL;DR: As a result of photolysis of aromatic bromo- and chlorohydrocarbons in benzene solution, products of replacement of the halogen atoms by a phenyl group were obtained.
Abstract: As a result of photolysis of aromatic bromo- and chlorohydrocarbons in benzene solution, products of replacement of the halogen atoms by a phenyl group were obtained.

1 citations

Journal ArticleDOI
TL;DR: The use of peroxydisulfate instead of the peroxysulfate-monovalent silver system as the oxidant favors the oxidative rearrangement of alkanal cyanohydrins into cyanoalkanoic acids due to a decrease in the competitive transformation into alkanoic acid.
Abstract: 1. Alkanal cyanohydrins (R(CH2)4CH(OH)CN (R=H, alkyl) are transformed into 4- and 5-cyanoalkanoic and alkanolc acids: RCH2CH(CN)CH2CH2COOH, RCH(CN)CH2CH2CH2COOH, and R(CH2)4·COOH, under the effect of peroxydisulfate ions on heating (60–80°C). 2. The use of peroxydisulfate instead of the peroxydisulfate-monovalent silver system as the oxidant favors the oxidative rearrangement of the alkanal cyanohydrins into cyanoalkanoic acids due to a decrease in the competitive transformation into alkanoic acids, and also permits obtaining cyanoalkanoic and alkanoic acids with a higher total yield. 3. The formation of the cyanohydrin cation-radical and its isomerization with 1,5- and 1,6-migration of the hydrogen atom are the most probable initial stages of the reaction of peroxydisulfates with alkanal cyanohydrins.

1 citations

Journal ArticleDOI
TL;DR: In this article, free-radical addition of dicarboxylic acid esters to α-olefins leads to the formation, In high yields, of α-alkyldicaroxyl acid ester.
Abstract: 1. Free-radical addition of dicarboxylic acid esters to α-olefins leads to the formation, In high yields, of α-alkyldicarboxylic acid esters. The reaction may be employed for the preparative synthesis of α-alkyidicarboxylic acids. 2. Carboxylic acids (or their esters) add on to esters of unsaturated acids with the formation of dicarboxylic acid esters.

1 citations

Journal ArticleDOI
TL;DR: In this paper, a mixture of α-hydroxy hydroperoxide (n = 0, 1, 2) and α,α-dihydroxy peroxide C2H5O2-CCH2C(OH)(CH3)-O-OC(OH)(CH3)CH2CO2C2C5 (n=0, 1.2) are generated selectively and enter into recombination, hydrogen transfer, and oxidation (when n=0) reactions.
Abstract: 1. Ethyl pyruvate and levulinate react with an ether solution of hydrogen peroxide, forming α-hydroxy hydroperoxides CH3C(OH)(OOH)-(CH2)nCOOC2H5 (where n=0, 2); acetoacetic ester gives a mixture of α-hydroxy hydroperoxide (n=1) and α,α′-dihydroxy peroxide C2H5O2-CCH2C(OH)(CH3)-O-OC(OH)(CH3)CH2CO2C2H5. 2. During the decomposition of the α-hydroxy hydroperoxides by the action of ferrous sulfate and ferrous chloride the radicals ·(CH2)nCOOC2H5 (n=0, 1, 2) are generated selectively and enter into recombination, hydrogen transfer, and oxidation (when n=0) reactions.

1 citations


Cited by
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[...]

08 Dec 2001-BMJ
TL;DR: There is, I think, something ethereal about i —the square root of minus one, which seems an odd beast at that time—an intruder hovering on the edge of reality.
Abstract: There is, I think, something ethereal about i —the square root of minus one. I remember first hearing about it at school. It seemed an odd beast at that time—an intruder hovering on the edge of reality. Usually familiarity dulls this sense of the bizarre, but in the case of i it was the reverse: over the years the sense of its surreal nature intensified. It seemed that it was impossible to write mathematics that described the real world in …

33,785 citations

Journal ArticleDOI
TL;DR: Recent progress in the field of organometallic cobalt-catalyzed C–H activation is reviewed until November 2015.
Abstract: Catalytic C–H activation has emerged as a powerful tool for sustainable syntheses. In the recent years, notable success was achieved with the development of cobalt-catalyzed C–H functionalizations with either in situ generated or single-component cobalt-complexes under mild reaction conditions. Herein, recent progress in the field of organometallic cobalt-catalyzed C–H activation is reviewed until November 2015.

953 citations

Journal ArticleDOI
TL;DR: This analysis comprehensively review all asymmetric transition-metal-catalyzed methodologies that are believed to proceed via an inner-sphere-type mechanism, with an emphasis on the nature of stereochemistry generation.
Abstract: The development of new methods for the direct functionalization of unactivated C–H bonds is ushering in a paradigm shift in the field of retrosynthetic analysis. In particular, the catalytic enantioselective functionalization of C–H bonds represents a highly atom- and step-economic approach toward the generation of structural complexity. However, as a result of their ubiquity and low reactivity, controlling both the chemo- and stereoselectivity of such processes constitutes a significant challenge. Herein we comprehensively review all asymmetric transition-metal-catalyzed methodologies that are believed to proceed via an inner-sphere-type mechanism, with an emphasis on the nature of stereochemistry generation. Our analysis serves to document the considerable and rapid progress within in the field, while also highlighting limitations of current methods.

648 citations