G. I. Nikishin

Bio: G. I. Nikishin is an academic researcher from Russian Academy of Sciences. The author has contributed to research in topics: Radical & Homolysis. The author has an hindex of 11, co-authored 280 publications receiving 540 citations.

The effect of electrolysis conditions on the oxidation of styrene in methanol

Abstract: Anodic oxidation of styrene (1) in methanol and the effect of the anion of the supporting electrolyte and of the anode material on this process have been studied. The most efficient conversion of1 into (1,2-dimethoxyethyl)benzene (2) occurs when the electrolysis is carried out with a platinum anode and with potassium fluoride or tetrabutylammonium tetrafluoroborate as the supporting electrolyte. Cleavage of the C-C σ bond in2 to give benzaldehyde dimethylacetal (3) is the most efficient at a graphite anode in the presence of sodium tosylate.

Synthesis of nine-, ten-, and fifteen-membered alkenolides by the oxidative cleavage of the bridging C = C bond in 2-oxabicycloalkenes

Abstract: Hydroperoxidation of C=C-bridged 2-oxabicycloalkenes in which the five- or six-membered oxacycle is fused with the five-, six-, or twelve-membered hydrocarbon ring was studied. The Cu(OAc)2-catalyzed decomposition of the resulting hydroperoxides afforded nine-, ten-, or fifteen-membered trans-alkenolides, respectively. The latter compounds were obtained as pairs of regioisomers, with the isomers in which the double bond is more remote from the ether oxygen atom predominating.

I and i

Abstract: There is, I think, something ethereal about i —the square root of minus one. I remember first hearing about it at school. It seemed an odd beast at that time—an intruder hovering on the edge of reality. Usually familiarity dulls this sense of the bizarre, but in the case of i it was the reverse: over the years the sense of its surreal nature intensified. It seemed that it was impossible to write mathematics that described the real world in …

Cobalt-Catalyzed C―H Activation

Abstract: Catalytic C–H activation has emerged as a powerful tool for sustainable syntheses. In the recent years, notable success was achieved with the development of cobalt-catalyzed C–H functionalizations with either in situ generated or single-component cobalt-complexes under mild reaction conditions. Herein, recent progress in the field of organometallic cobalt-catalyzed C–H activation is reviewed until November 2015.

Catalytic Enantioselective Transformations Involving C-H Bond Cleavage by Transition-Metal Complexes.

Abstract: The development of new methods for the direct functionalization of unactivated C–H bonds is ushering in a paradigm shift in the field of retrosynthetic analysis. In particular, the catalytic enantioselective functionalization of C–H bonds represents a highly atom- and step-economic approach toward the generation of structural complexity. However, as a result of their ubiquity and low reactivity, controlling both the chemo- and stereoselectivity of such processes constitutes a significant challenge. Herein we comprehensively review all asymmetric transition-metal-catalyzed methodologies that are believed to proceed via an inner-sphere-type mechanism, with an emphasis on the nature of stereochemistry generation. Our analysis serves to document the considerable and rapid progress within in the field, while also highlighting limitations of current methods.