Author
G. Pneumatikakis
Bio: G. Pneumatikakis is an academic researcher from National and Kapodistrian University of Athens. The author has contributed to research in topics: Denticity & Palladium. The author has an hindex of 13, co-authored 37 publications receiving 514 citations.
Topics: Denticity, Palladium, Aqueous solution, Circular dichroism, Nucleoside
Papers
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71 citations
TL;DR: In this paper, the results indicate that the coordination sites strongly depend upon the pH of the solutions and the stoichiometry of the metal to ligand ratio, and suggested possible structures of the isolated complexes with respect to their IR spectra.
47 citations
TL;DR: In this paper, the interaction of 2-benzoylpyridine with first row transition metal ions is studied in organic solvents and in the solid state and the isolated complexes are characterized by elemental analyses, magnetic susceptibility, conductivity measurements, IR spectra and UV-vis electronic spectra.
39 citations
TL;DR: The catalytic decomposition of hydrogen peroxide by Cu(II) complexes with polymers bearing L-alanine and glycylglycine in their side chain was studied in alkaline aqueous media and the trend in catalytic efficiency is in the order PGlygly>PAla.
Abstract: The catalytic decomposition of hydrogen peroxide by Cu(II) complexes with polymers bearing L-alanine (PAla) and glycylglycine (PGlygly) in their side chain was studied in alkaline aqueous media. The reactions were of pseudo-first order with respect to [
38 citations
TL;DR: Covalent binding between these nucleotides and altromycin B takes place and explain the multiple binding mode suggested by the studies of the interaction of altroB and its complexes with DNA.
37 citations
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TL;DR: In this paper, the reaction of ruthenium(II) complexes with bidentate Schiff base ligands derived by condensing salicylaldehyde with aniline, o-, m- or p-toluidine has been carried out.
Abstract: The reactions of ruthenium(II) complexes, [RuHCl(CO)(PPh3)2(B)] [B = PPh3, pyridine (py) or piperidine (pip)], with bidentate Schiff base ligands derived by condensing salicylaldehyde with aniline, o-, m- or p-toluidine have been carried out. The products were characterised by analytical, i.r., electronic, 1H-n.m.r. and 31P-n.m.r. spectral studies and are formulated as [RuCl(CO)(L)(PPh3)(B)] (L = Schiff base anion; B = PPh3, py or pip). An octahedral structure has been tentatively proposed for the new complexes. The Schiff bases and the new complexes were tested in vitro to evaluate their activity against the fungus Aspergillus flavus.
573 citations
TL;DR: A review of the investigations undertaken into platinum-IV antitumour compounds since Barnett Rosenberg first noted the activity of platinum(IV) complexes is given in this article. But the bioinorganic chemistry of these compounds has not previously been reviewed, and the purpose here is to provide insight into the requirements for the antitumours activity of these complexes.
552 citations
TL;DR: In this article, the reactions of nanomolar concentrations of Cu(I) and Cu(II) with H 2 O 2 have been investigated in 2.0mM NaHCO 3 and 0.7m NaCl at pH 8.0.
475 citations
TL;DR: The combined results of NMR spectroscopy, X-ray crystallography, and various biochemical tools provide incontrovertible evidence that dinuclear complexes are favorably poised to bind to purine nucleobases, DNA fragments, and double-stranded DNA.
Abstract: This Account summarizes the DNA binding properties of anticancer active dinuclear Rh, Re, and Ru compounds. The combined results of NMR spectroscopy, X-ray crystallography, and various biochemical tools provide incontrovertible evidence that dinuclear complexes are favorably poised to bind to purine nucleobases, DNA fragments, and double-stranded DNA. Moreover, direct DNA photocleavage in vitro is effected by dirhodium compounds in the presence of electron acceptors in solution or directly attached to the dirhodium core. This research has provided valuable insight in the interactions of dinuclear compounds with DNA, knowledge that is an excellent backdrop for rational design of promising dinuclear drugs.
420 citations
TL;DR: In this article, the anti-tumor, anti-fungal and anti-microbial properties of new Pd(II) complexes are compared with similar properties of other metals.
407 citations