G
G. Truitt
Researcher at Hoffmann-La Roche
Publications - 1
Citations - 237
G. Truitt is an academic researcher from Hoffmann-La Roche. The author has contributed to research in topics: Lung cancer & Prinomastat. The author has an hindex of 1, co-authored 1 publications receiving 235 citations.
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Broad antitumor and antiangiogenic activities of AG3340, a potent and selective MMP inhibitor undergoing advanced oncology clinical trials.
David R. Shalinsky,John Brekken,H. Zou,Charles D. McDermott,Peter A. Forsyth,Dylan R. Edwards,S. Margosiak,S. Bender,G. Truitt,Alexander W. Wood,Nissi Varki,Krzysztof Appelt +11 more
TL;DR: In combination, AG3340 enhanced the efficacy of these cytotoxic agents without altering drug tolerance, and decreased the number of murine melanoma lesions arising in the lung in an intravenous metastasis model when given in combination with carboplatin or Taxol.