G
G W Butcher
Researcher at Agricultural and Food Research Council
Publications - 23
Citations - 3239
G W Butcher is an academic researcher from Agricultural and Food Research Council. The author has contributed to research in topics: Antigen & Major histocompatibility complex. The author has an hindex of 17, co-authored 23 publications receiving 3214 citations.
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Journal ArticleDOI
Antibodies to major histocompatibility antigens produced by hybrid cell lines.
TL;DR: FUSION between myeloma cells and spleen cells from immunised donors has been shown to be a successful method of deriving homogeneous anti-SRBC (anti-sheep red blood cell) and anti-TNP antibodies.
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Effect of polymorphism of an MHC-linked transporter on the peptides assembled in a class I molecule
Simon J. Powis,Deverson Ev,Coadwell Wj,Ciruela A,Ciruela A,Huskisson Ns,Smith H,G W Butcher,Jonathan C. Howard +8 more
TL;DR: It is demonstrated that a complex polymorphism in one of the major histocompatibility complex-encoded putative peptide-transporter genes is associated with an altered spectrum of bound peptides.
Journal ArticleDOI
Selectivity of MHC-encoded peptide transporters from human, mouse and rat
Frank Momburg,Joost Roelse,Jonathan C. Howard,G W Butcher,Günter J. Hämmerling,Jacques Neefjes +5 more
TL;DR: The amino- and carboxy-terminal and the penultimate amino-acid residues of model peptides are substituted to show that these residues influence the efficiency of transport and correspond with the predominant peptide binding profiles of mouse and human class I molecules.
Journal Article
Differential expression of Ia and Ia-associated invariant chain in mouse tissues after in vivo treatment with IFN-gamma.
Frank Momburg,Norbert Koch,Peter Möller,Gerhard Moldenhauer,G W Butcher,Günter J. Hämmerling +5 more
TL;DR: The data demonstrate that IFN-gamma applied i.v. is a potent inducer or enhancer of Ia antigens and invariant chain in a variety of cell types.
Journal Article
Subsets of null and gamma delta T-cell receptor+ T lymphocytes in the blood of young pigs identified by specific monoclonal antibodies.
TL;DR: Several properties of this new antigen complex specific to pig Null T cells show that it is distinct from the ruminant T19 complex.