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Gabriella D'Orazi

Researcher at University of Chieti-Pescara

Publications -  129
Citations -  12299

Gabriella D'Orazi is an academic researcher from University of Chieti-Pescara. The author has contributed to research in topics: Cancer cell & Cancer. The author has an hindex of 39, co-authored 114 publications receiving 9825 citations. Previous affiliations of Gabriella D'Orazi include Sapienza University of Rome & University of L'Aquila.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
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Apoptosis as anticancer mechanism: function and dysfunction of its modulators and targeted therapeutic strategies

Giuseppa Pistritto, +4 more
TL;DR: The role of the fundamental regulators of apoptosis are highlighted and how their deregulation, including activation of anti-apoptotic factors or inactivation of pro-ap optotic factors ends up in cancer cell resistance to therapies.
Journal ArticleDOI

Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis

Gabriella D'Orazi, +13 more
- 01 Jan 2002 - 
TL;DR: Homeodomain-interacting protein kinase-2 (HIPK2), a member of a novel family of nuclear serine/threonine kinases, binds to and activates p53 by directly phosphorylating it at Ser 46 and results in the targeted subcellular localization of p53 and initiation of apoptosis.
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Type IV collagenase(s) and TIMPs modulate endothelial cell morphogenesis in vitro

H. William Schnaper, +12 more
- 01 Aug 1993 - 
TL;DR: It is demonstrated that gelatinase/type IV collagenase activity is important in endothelial cell morphogenesis on Matrigel, and a role for collagenases in formation of new capillaries in vivo is suggested.