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Gaofeng Feng

Bio: Gaofeng Feng is an academic researcher from Shaoxing University. The author has contributed to research in topics: Radical & Catalysis. The author has an hindex of 2, co-authored 3 publications receiving 35 citations.

Papers
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Journal ArticleDOI
TL;DR: The first visible-light-mediated photoredox oxidative approach for generating carbamoyl radicals from oxamic acids is disclosed in this paper, which is compatible with a variety of oxamic acid and electron-deficient alkenes, and a wide variety of 3,4dihydroquinolin-2(1H)-ones were prepared.

42 citations

Journal ArticleDOI
TL;DR: In this article, a novel visible-light-induced α-amino C-H bond arylation protocol, without a photoredox catalyst, has been disclosed, which does not require any transition metal, oxidant, or exclusion of oxygen or moisture.

15 citations

Journal ArticleDOI
01 Sep 2020-Synlett
TL;DR: An efficient silver-catalyzed tandem decarboxylative radical addition/cyclization of oxamic acids with alkenes has been developed in this paper, which provides a novel and straightforward protocol toward a variety of 4-aryl-3,4-dihydroquinolin-2(1H)-ones, 4-(α-carbonyl)-3, 4-D-Dihydron-2-1H-ones, and quinolin-1-H -ones in aqueous solution.
Abstract: An efficient silver-catalyzed tandem decarboxylative radical addition/cyclization of oxamic acids with alkenes has been developed. This method provides a novel and straightforward protocol toward a variety of 4-aryl-3,4-dihydroquinolin-2(1H)-ones, 4-(α-carbonyl)-3,4-dihydroquinolin-2(1H)-ones, and quinolin-2(1H)-ones in aqueous solution.

7 citations


Cited by
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Journal ArticleDOI
TL;DR: The most recent and significant developments in the radical activation and functionalization of carbon-carbon bonds are summarized, with an emphasis on both synthetic outcomes and reaction mechanisms, and how these radical C-C bond cleavage reactions enable challenging transformations.
Abstract: In recent years, radical C–C bond cleavage reactions have been increasingly understood and used to perform transformations that complement traditional ionic processes. However, to date radical C–C bond cleavage/functionalization reactions have not been the subject of a dedicated review. Herein we summarize the most recent and significant developments in the radical activation and functionalization of carbon–carbon bonds, with an emphasis on both synthetic outcomes and reaction mechanisms, and highlight how these radical C–C bond cleavage reactions enable challenging transformations.

214 citations

Journal ArticleDOI
TL;DR: Recent progress of visible-light-driven acyl radical generation using transition metal photoredox catalysts, metallaphotocatalysts, hypervalent iodine catalysts or organic photocatalyst is summarized.
Abstract: Visible-light photoredox catalysis enables easy access to acyl radicals under mild reaction conditions. Reactive acyl radicals, generated from various acyl precursors such as aldehydes, α-keto acids, carboxylic acids, anhydrides, acyl thioesters, acyl chlorides, or acyl silanes, can undergo a diverse range of synthetically useful transformations, which were previously difficult or inaccessible. This review summarizes the recent progress on visible-light-driven acyl radical generation using transition-metal photoredox catalysts, metallaphotocatalysts, hypervalent iodine catalysts or organic photocatalysts. 1 Introduction 2 The Scope of This Review 3 Aldehydes as a Source of Acyl Radicals 4 α-Keto Acids as a Source of Acyl Radicals 5 Carboxylic Acids as a Source of Acyl Radicals 6 Anhydrides as a Source of Acyl Radicals 7 Acyl Thioesters as a Source of Acyl Radicals 8 Acyl Chlorides as a Source of Acyl Radicals 9 Acyl Silanes as a Source of Acyl Radicals 10 Conclusions and Future Outlook

129 citations

Journal ArticleDOI
TL;DR: In this article, the photochemical/photocatalyzed pathways that allow the introduction of the acyl group in aromatics, alkenes and alkynes are presented.

109 citations

Journal ArticleDOI
TL;DR: Various 3-acyl quinoxalin-2(1H)-ones could be efficiently obtained in good yields with excellent functional group compatibility.
Abstract: A mild and facile visible-light-mediated strategy has been proposed for the synthesis of 3-acyl quinoxalin-2(1H)-ones through acridine red catalyzed aerobic oxidative decarboxylative acylation of α-oxo-carboxylic acids with quinoxalin-2(1H)-ones at room temperature in air. Various 3-acyl quinoxalin-2(1H)-ones could be efficiently obtained in good yields with excellent functional group compatibility.

88 citations

Journal ArticleDOI
TL;DR: A novel visible-light-induced and Rose Bengal catalyzed strategy has been developed for the synthesis of α-ketoamides via decarboxylative acylations of isocyanides with α-oxocarboxylic acids and water under mild conditions.

57 citations