G
Gaolin Liang
Researcher at Southeast University
Publications - 189
Citations - 10082
Gaolin Liang is an academic researcher from Southeast University. The author has contributed to research in topics: Chemistry & Medicine. The author has an hindex of 45, co-authored 158 publications receiving 7689 citations. Previous affiliations of Gaolin Liang include University of Science and Technology of China & Fudan University.
Papers
More filters
Journal ArticleDOI
Enzymatic hydrogelation of small molecules.
Zhimou Yang,Gaolin Liang,Bing Xu +2 more
TL;DR: In this Account, the design and application of enzyme-catalyzed or -regulated formation of supramolecular hydrogels that offer a new strategy for detecting the activity of enzymes, screening for enzyme inhibitors, typing bacteria, drug delivery systems, and controlling the fate of cells are illustrated.
Journal ArticleDOI
Using a Kinase/Phosphatase Switch to Regulate a Supramolecular Hydrogel and Forming the Supramolecular Hydrogel in Vivo
TL;DR: A kinase/phosphatase switch is used to control the phosphorylation and dephosphorylation of the hydrogelator and to regulate the formation of supramolecular hydrogels, which promises a new way to design and construct biomaterials.
Journal ArticleDOI
Oridonin is a covalent NLRP3 inhibitor with strong anti-inflammasome activity.
Hongbin He,Hua Jiang,Yun Chen,Jin Ye,Aoli Wang,Chao Wang,Qingsong Liu,Gaolin Liang,Xianming Deng,Wei Jiang,Rongbin Zhou +10 more
TL;DR: Ori can be covalently linked to NLRP3 to prevent assembly of theNLRP3 inflammasome, and to ameliorate inflammation in several mouse disease models, and could serve as a lead for developing new therapeutics against NL RP3-driven diseases.
Journal ArticleDOI
FePt@CoS2 yolk-shell nanocrystals as a potent agent to kill HeLa cells
TL;DR: The exceptionally high toxicity of FePt@CoS(2) yolk-shell nanocrystals (about 7 times higher than that of cisplatin in terms of Pt) may lead to a new design of an anticancer nanomedicine.
Journal ArticleDOI
A biocompatible condensation reaction for controlled assembly of nanostructures in living cells
TL;DR: A condensation reaction between 1,2-aminothiol and 2-cyanobenzothiazole that occurs in vitro and in living cells under the control of pH, disulfide reduction and enzymatic cleavage is reported.