Showing papers by "Gaurav Sharma published in 1983"
Journal Article•
TL;DR: Even in the patients at high risk for graft occlusion, i.e., those who had small recipient coronary arteries and poor graft flows, patency rates were not improved by the antiplatelet agents.
Abstract: To develop a way to prevent the occlusion of the aortocoronary saphenous vein bypass grafts, we conducted a prospective, randomized, double-blind trial in 176 patients, some of whom received aspirin alone (975 mg/day) and some of whom took a combination of aspirin and dipyridamole (225 mg/day), and compared them with a parallel control group. Therapy was started 3 to 5 days after surgery. Follow-up angiography was performed in 142 patients (80%) at 1 year. Graft patency in the aspirin group (78%) was not significantly different from that in the aspirin-dipyridamole group (83%) or the control group (80%). Even in the patients at high risk for graft occlusion, i.e., those who had small recipient coronary arteries and poor graft flows, patency rates were not improved by the antiplatelet agents. When administered 3 to 5 days after surgery, aspirin alone or in combination with dipyridamole does not improve graft patency.
106 citations
TL;DR: The mortality of undiagnosed and therefore untreated PE is relatively high, ranging from about 18% to 35%,1whereas, once diagnosed and treated, a substantial reduction to about 8% occurs.
Abstract: PULMONARY embolism (PE) is a common complication that usually afflicts patients who are hospitalized for other medical or surgical problems. Its continued prevalence seems to be the result of increasing numbers of older and sicker patients who are hospitalized and subjected to longer periods of bed rest and more complex operations. Although the true incidence of PE is not known, a reasonable estimate can be made from various studies that suggest that fatal PE occurs in about three to five patients per 1,000 inpatients in a general hospital population, including both hipsurgery patients and patients with malignant neoplasms undergoing surgical procedures, and nonfatal PE occurs in about 15 to 20 patients per 1,000 inpatients. The mortality of undiagnosed and therefore untreated PE is relatively high, ranging from about 18% to 35%,1whereas, once diagnosed and treated, a substantial reduction to about 8% occurs. This observation underscores the importance of
50 citations
TL;DR: Best surgical results can be predicted when the internal diameter of the recipient vessel is 2.5 mm or more, graft flow is 100 ml/min or more and the regional left ventricle moves well, and the better the graft patency.
17 citations
TL;DR: It is concluded that venousthromboembolism associated with gynecologic surgery is associated with a higher risk of pulmonary embolism than previously thought.
Abstract: Justin JR, GibsonRJ, Felix WRJr, PopkyGL,ParkerJA,Ipsen J: Risk assessment of pulmonary embolism by multivariateanalysis. Arch Surg 114: 188, 197913. GentonE, Turpie AGC:Venousthromboembolism associated withgynecologic surgery. Clin Obstet Gynecol 23: 209, 198014. MoserKM,LeMoineJR: Is embolic risk conditioned bylocation ofdeep venous thrombosis? Ann Intern Med 94: 439, 198115. Prescott SM, Richard KL, TikoffG, Armstrong JD
2 citations
TL;DR: Venous thrombosis and pulmonary embolism occurring at close intervals in spinal cord injury patients is found to be associated with high blood pressure and high creatinine levels.
Abstract: Venous thrombosis and pulmonary embolism occurring at close intervals in spinal cord injury patients
2 citations