Showing papers by "Gaurav Sharma published in 1992"

Cause and impact of pulmonary hypertension in isolated aortic stenosis on operative mortality for aortic valve replacement in men

Abstract: Significant pulmonary hypertension is considered to be an infrequent finding in patients with aortic stenosis (AS).1,2 When present, it is usually thought to be related to either markedly depressed left ventricular systolic function, or associated mitral valve or pulmonary disease.3,4 However, there are very few reports that examined the pathogenesis and clinical significance of pulmonary hypertension in isolated AS. Therefore, the objective of this study was to determine the incidence and pathophysiology of pulmonary hypertension in isolated AS, and its effect on operative mortality for aortic valve replacement.

Circadian rhythm of pulmonary embolism in patients with acute spinal cord injury.

Abstract: Thrombotic events with a circadian rhythm have been described during the past several years, with onset of myocardial infarction and stroke predominating in the morning hours.1,2 Recently, a circadian rhythm for pulmonary thromboembolism has been reported; the onset of these events also prevailed in the morning hours.3 Patients with spinal cord injury are known to be at risk for pulmonary embolism during the early course of their paralysis.4 Because all of the patients with acute spinal cord injury are a hospitalized population in whom the onset of pulmonary embolic events can be observed and documented, we examined the issue of a circadian rhythm for pulmonary embolism.