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Author

Gaurav Sharma

Other affiliations: Northeastern University, D. E. Shaw & Co., Hewlett-Packard  ...read more
Bio: Gaurav Sharma is an academic researcher from Shenzhen University. The author has contributed to research in topics: Medicine & Photocatalysis. The author has an hindex of 82, co-authored 1244 publications receiving 31482 citations. Previous affiliations of Gaurav Sharma include Northeastern University & D. E. Shaw & Co..


Papers
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TL;DR: Recurrent pulmonary emboli resulted in chronic pulmonary hypertension and eventual death in a patient with chronic tetraplegia and was described in an unusual case of progressive pulmonary hypertension in a chronically paralyzed spinal cord injury patient.
Abstract: Case report. To describe an unusual case of progressive pulmonary hypertension due to recurrent pulmonary embolism in a chronically paralyzed spinal cord injury patient. Veterans Administration Hospital, West Roxbury, MA, USA. A 57-year-old man, tetraplegic, sensory incomplete and motor complete for 30 years due to a diving accident, complained of lightheadedness and shortness of breath intermittently for 7 years. Examination during the latest episode revealed anxiety, confusion, respirations 28 per min, blood pressure 80/60 mmHg, and arterial pH 7.41, 28 mmHg, 95 mmHg on 2 l of oxygen. A chest film 2 weeks earlier had revealed a right-sided cutoff of pulmonary vasculature; the current film showed right-sided pleural effusion. Review of EKGs showed a trend of increasing right axis deviation with recovery and recurrences during the previous 9 years and a current incomplete right bundle branch block with clockwise rotation and inverted T waves in V1–4. Computerized tomography with contrast material revealed small pulmonary emboli, but only in retrospect. The patient died shortly after scanning. The pulmonary arteries were free of thromboemboli on gross examination but medium and small-sized arteries were constricted or obliterated with thrombotic material microscopically. The estimated ages of the thromboemboli ranged from days to years. The right ventricle was hypertrophied; the coronary arteries were patent. Recurrent pulmonary emboli resulted in chronic pulmonary hypertension and eventual death in a patient with chronic tetraplegia.

6 citations

Journal ArticleDOI
TL;DR: This paper presents a formal model tailored to study auction systems that facilitate anonymity, as well as a generic protocol for achieving bid confidentiality and bidder anonymity using existing cryptographic primitives such as designated verifier ring signature.
Abstract: In a competitive market, online auction systems enable optimal trading of digital products and services. Bidders can participate in existing blockchain-based auctions while protecting the confidentiality of their bids in a decentralized, transparent, secure, and auditable manner. However, in a competitive market, parties would prefer not to disclose their interests to competitors, and to remain anonymous during auctions. In this paper, we firstly analyze the specific requirements for blockchain-based anonymous fair auctions. We present a formal model tailored to study auction systems that facilitate anonymity, as well as a generic protocol for achieving bid confidentiality and bidder anonymity using existing cryptographic primitives such as designated verifier ring signature. We demonstrate that it is secure using the security model we presented. Towards the end, we demonstrate through extensive simulation results on Ethereum blockchain that the proposed protocol is practical and has minimal associated overhead. Furthermore, we discuss the complexity and vulnerabilities that a blockchain environment might introduce during implementation.

6 citations

Journal ArticleDOI
TL;DR: In this paper, the impact of La2O3 promoter loading on alumina-supported cobalt catalysts was investigated in terms of physicochemical properties and catalytic performance for CO2 reforming of methane (CRM) at stoichiometric CH4/CO2 ratio and 1023 K. 5%La loading was an optimal promoter content for reactant conversions as well as yield of H2 and CO.
Abstract: The impact of La2O3 promoter loading on alumina-supported cobalt catalysts was investigated in terms of physicochemical properties and catalytic performance for CO2 reforming of methane (CRM) at stoichiometric CH4/CO2 ratio and 1023 K. Both Co3O4 (with crystal size: 5.2–8.4 nm) and La2O3 nanoparticles were finely dispersed on support surface. The promotional La2O3 effect could noticeably increase CH4 and CO2 conversions to 29.3% and 17.3%, correspondingly due to improved basic site concentration and decreasing crystallite size of active metal in association with promoter addition. 5%La loading was an optimal promoter content for reactant conversions as well as yield of H2 and CO. 5%La-10%Co/Al2O3 also exhibited the highest resistance to carbon deposition owing to the basic nature, redox feature and oxygen vacancy of La2O3 dopant. Notably, the H2/CO ratio obtained within 0.84–0.98 is preferable for Fischer-Tropsch reaction in downstream to yield liquid hydrocarbon fuels.

6 citations

Journal ArticleDOI
TL;DR: A novel methodology for accurately registering a vector road map to wide area motion imagery (WAMI) gathered from an oblique perspective by exploiting the local motion associated with vehicular movements is presented.
Abstract: We present a novel methodology for accurately registering a vector road map to wide area motion imagery (WAMI) gathered from an oblique perspective by exploiting the local motion associated with vehicular movements. Specifically, we identify and compensate for global motion from frame-to-frame in the WAMI which then allows ready detection of local motion that corresponds strongly with the locations of moving vehicles along the roads. Minimization of the chamfer distance between these identified locations and the network of road lines identified in the vector road map provides an accurate alignment between the vector road map and the WAMI image frame under consideration. The methodology provides a significant improvement over the approximate geo-tagging provided by on-board sensors and effectively side-steps the challenge of matching features between the completely different data modalities and viewpoints for the vector road map and the captured WAMI frames. Results over a test WAMI dataset indicate the effectiveness of the proposed methodology: both visual comparison and numerical metrics for the alignment accuracy are significantly better for the proposed method as compared with existing alternatives. Introduction Recent technological advances have made available number of airborne platforms for capturing imagery [1,2]. One of the specific areas of emerging interest for applications is Wide Area Motion Imagery (WAMI) where images at temporal rates of 1–2 frames per-second can be captured for relatively large areas that span substantial parts of a city while maintaining adequate spatial detail to resolve individual vehicles [3]. WAMI platforms are becoming increasingly prevalent and the imagery they generate are also feeding a corresponding thrust in large scale visual data analytics. The effectiveness of such analytics can be enhanced by combining the WAMI with alternative sources of rich geo-spatial information such as road maps. In this paper we focus on near real-time registration of vector road-map data to WAMI and propose a novel methodology that exploits vehicular motion for accurate and computationally efficient alignment. Registering road map vector data with aerial imagery leads to rich source of geo-spatial information, which can be used for many applications. One application of interest is moving vehicle detection and tracking in wide area motion imagery (WAMI). By registering the road network to aerial imagery, we can easily filter out the false detections that occurred off roads. Another interesting application is to detect and track a suspicious vehicle that goes off road. These applications depend on accurate road network alignment with the aerial imagery, which is the focus of this paper. In general, successive WAMI video frames are related by both global and local motions. The global motion arises from the camera movement due to the aerial platform movement, and it can be parameterized as a homography between the spatial coordinates for successive frames under the assumption that the captured scene is planar. The local motion arises due to the local movement of objects in the scene. Local motion in WAMI for urban scenes is dominated by vehicle movements on the network of roads within the captured area. We exploit these vehicular movements to develop an effective registration scheme for aligning vector road maps data with the captured WAMI frame. (b) (a) Figure 1: Road network alignment. (a) using only aerial frame metadata, (b) using our proposed algorithm. WAMI frames are usually captured from platform equipped with Global Positioning System (GPS) and Inertial Navigation System (INS) which provide location and orientation information that are usually stored with the aerial image as meta-data. This meta-data can be used to align a road network extracted from external Geographic Information System (GIS) source. However, as illustrated by the example in Fig. 1(a), the accuracy of the meta-data is limited and only provides an approximate alignment. Registering an aerial image directly with a geo-referenced vector road map is a challenging task because of the differences in the nature of the data in the two formats: in one case the data consists of image pixel values whereas in the other it is described as lines/curves connecting a series of points. Because of the inherent differences in the data formats, one cannot readily define low/mid-level features that are invariant to the representations and can be used for registration as conventional feature detectors, such as SIFT (Scale-Invariant Feature Transform) [4], are used for finding corresponding points in images. For static imagery, a lot of research has been done for aligning vector road maps to aerial imagery, normally referred to as the process of conflating. In general, conflation refers to a process that fuses spatial representation from multiple data sources to obtain a new superior representation. In [5–7], road vector data are aligned with an aerial image by matching the road intersection points in both representations. The crucial element in these prior works is the detection of road intersections from the aerial image. With the availability of hyper-spectral aerial imagery, spectral properties and contextual analysis are used in [5] to detect these road intersections in the aerial scene. However, road segmentation is not robust for different natural scenes specially when roads are obscured by shadows from trees and nearby buildings. In [6], a Bayes classifier used to classify pixels as on-road or off-road, then a localized template matching used to detect the road intersections. However, to get a reasonable accuracy with the Bayes classifier, a large number of manually labeled training pixels is required for each data set. In [7], corner detection is used to detect the road intersections, which is not reliable specially in high resolution aerial images, that contain enough wide roads where the simple corner detection fails. Work on registration of (non-static) WAMI frames to geo©2016 Society for Imaging Science and Technology DOI: 10.2352/ISSN.2470-1173.2016.3.VSTIA-520 IS&T International Symposium on Electronic Imaging 2016 Video Surveillance and Transportation Imaging Applications 2016 VSTIA-520.1 referenced vector road maps has received comparatively less attention, even though the capability for performing such registration in a computationally efficient manner is crucial for a number real/near real-time analysis applications for WAMI, as already mentioned. Some of the prior work on this problem overcomes the problem posed by fundamentally different modalities of the WAMI and vector datasets by using an auxiliary geo-referenced image that is already aligned with the vector road map. The aerial image frames are then aligned to the auxiliary geo-referenced image by using conventional image feature matching methods. For example, in [8], for the purpose of vehicular tracking, the aerial frame is geo-registered with a geo-reference image and then a GIS database is used for road network extraction. This road network is used to regularize the matching of the current vehicle detections to the previous existing vehicular tracks. In an alternative approach that relies on 3D geometry, in [9], SIFT is used to detect correspondences between the ground features from a small footprint aerial video frame and geo-referenced image. This geo-registration helps to estimate the camera pose and depth map for each frame, and this depth map is used to segment the scene into building, foliage, and roads using a multi-cue segmentation framework. The process is computationally intensive and the use of the auxiliary georeferenced image is still plagued by problems with identification of corresponding feature points because of the illumination changes, different capturing times, severe view point change in aerial imagery, and occlusion. State of the art feature point detectors and descriptors such as SIFT (Scale-Invariant Feature Transform) [4], and SURF (Speeded Up Robust Features) [10], often find many spurious matches that cause robust estimators such as RANSAC [11] to fail when estimating a homography. Also, these methods cannot work directly if the aerial video frames have a different modality (infra-red for example) than the geo-referenced image. Last, but not least, a single homography represents the relation between two images when the scene is close to planar [12]. In WAMI, aerial video frames usually taken from oblique camera array to cover large ground area from moderate height and the scene usually contains non ground objects such as building, trees, and foliage. Thus the planar assumption does not necessarily hold across the entire imagery, although it is not unreasonable for the road network. In this paper, we propose an algorithm that accurately aligns a vector road network to WAMI aerial video frames by detecting the locations of moving vehicles and aligning the detected vehicle locations with the network of roads in the vector road map. The vehicle locations are readily detected by performing frame-to-frame registration using conventional image feature matching methods and computing compensated frame differences to identify local motion that differs significantly from the overall global motion resulting from the camera movement. Such local motion is predominantly due to moving vehicles and the regions where the compensated frame differences are large correspond (predominantly) to vehicle locations. We align the WAMI frames to the vector road map by estimating the projective transformation parameters that, after appropriate application of the transformation, minimize a metric defined as the sum of minimum squared distances from the detected vehicle locations to the corresponding nearest points on the network of roads. This metric is the well known chamfer distance, which can be efficiently computed via the distance transform [13]. The chamfe

6 citations

Journal Article
TL;DR: Approval of the efficacy of different herbicides on potato from 1996 to 1998 found that atrazine and pendimethalin were more effective on broadleaf weeds whereas alachlor, metolachlor and isoproturon were moreeffective on grassy weeds.
Abstract: Field experiments were carried out to assess the efficacy of different herbicides on potato from 1996 to 1998 at Highland Agricultural Research and Extension Centre, Kukumseri (HP). Atrazine and pendimethalin were more effective on broadleaf weeds whereas alachlor, metolachlor and isoproturon were more effective on grassy weeds. Pre-emergence application of metolachlor 1.5 kg/ha recorded the highest tuber yield (265.9 q/ha) which was at par with atrazine 0.0-1.25 kg/hal, isoproturon (1.25-1.5 kg/ha), alachlor 1.5 kg/ha, pendimethalin 1.2 kg/ha and fluchloralin 1.35 kg/ha. Application of atrazine 1.25 kg/ha, isoproturon (1.25-1.5 kglha), metolachlor 1.5 kg/ha and pendimethalin 1.2 kg/ha proved significantly better than twice hand weeding and hoeing. Uncontrolled weed growth caused 55.3, 47.2 and 45.7 per cent reduction in tuber yield as compared to the application of metolachlor 1.5 kg/ha, hand weeding twice and farmers' practice, respectively.

6 citations


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08 Dec 2001-BMJ
TL;DR: There is, I think, something ethereal about i —the square root of minus one, which seems an odd beast at that time—an intruder hovering on the edge of reality.
Abstract: There is, I think, something ethereal about i —the square root of minus one. I remember first hearing about it at school. It seemed an odd beast at that time—an intruder hovering on the edge of reality. Usually familiarity dulls this sense of the bizarre, but in the case of i it was the reverse: over the years the sense of its surreal nature intensified. It seemed that it was impossible to write mathematics that described the real world in …

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TL;DR: SPAdes as mentioned in this paper is a new assembler for both single-cell and standard (multicell) assembly, and demonstrate that it improves on the recently released E+V-SC assembler and on popular assemblers Velvet and SoapDeNovo (for multicell data).
Abstract: The lion's share of bacteria in various environments cannot be cloned in the laboratory and thus cannot be sequenced using existing technologies. A major goal of single-cell genomics is to complement gene-centric metagenomic data with whole-genome assemblies of uncultivated organisms. Assembly of single-cell data is challenging because of highly non-uniform read coverage as well as elevated levels of sequencing errors and chimeric reads. We describe SPAdes, a new assembler for both single-cell and standard (multicell) assembly, and demonstrate that it improves on the recently released E+V-SC assembler (specialized for single-cell data) and on popular assemblers Velvet and SoapDeNovo (for multicell data). SPAdes generates single-cell assemblies, providing information about genomes of uncultivatable bacteria that vastly exceeds what may be obtained via traditional metagenomics studies. SPAdes is available online ( http://bioinf.spbau.ru/spades ). It is distributed as open source software.

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