Gaurav Sharma

Bio: Gaurav Sharma is an academic researcher from Shenzhen University. The author has contributed to research in topics: Medicine & Photocatalysis. The author has an hindex of 82, co-authored 1244 publications receiving 31482 citations. Previous affiliations of Gaurav Sharma include Northeastern University & D. E. Shaw & Co..

Self-Assertive Generic UVM Testbench for Advanced Verification of Bridge IPs

Abstract: This work focuses on the implementation of Universal Verification Methodology (UVM) on bridge protocols along with the conjunction of advanced verification environment. Bridge devices are helpful in joining two separate network device to establish a communication link in between them. This proposed testbench reusable environment is capable of verifying all bridge devices and improved result as compared to System Verilog testbench. As a case study, this paper takes ARM-Advanced High-Performance Bus (AHB) to Advanced eXtensible Interface (AXI4) Bridge v3.0 under consideration to prove the test results for bridge devices. The advanced verification testbench incorporates the illustrations regarding C.P.U timings, simulation timings, and functional coverage to check further improvement of Design functionality. The self-checking mechanism using assertions improves the quality of UVM check by shortening time to debug and reducing time to cover for the in-depth understanding of test case output.

In-situ calibration of accelerometers in body-worn sensors using quiescent gravity

Abstract: As the cost, size and power required by sensor devices decrease, an increasing range of applications are possible. We focus on the application of tracking accelerometer data from body worn sensors over long durations in health monitoring applications. Body worn sensors must be compact for the convenience of the patient and low power to support extended operation, but these benefits can come at the cost of accuracy. To mitigate this loss of accuracy we first examine the ability of calibration to improve accuracy. Next we propose an in-situ method for calibrating the accelerometers using the quiescent acceleration due to gravity as a calibration signal. This in-situ calibration uses only the stored data from the duration the sensor is worn by the patient and does not require any extra procedures or measurements from the physical sensor devices. Compared to a manual three-axis calibration technique, the proposed calibration can be applied to data without the need for specific calibration procedures or even access to the original sensor and provides comparable or better accuracy.

Clinical and angiographic profiles and six months outcomes of smokers with acute ST segment elevation myocardial infarction undergoing primary percutaneous coronary angioplasty.

Abstract: Background Outcomes of primary percutaneous coronary intervention (PCI) for acute STEMI (ST-segment elevation myocardial infarction) in smokers are expected to be better than non-smokers as for patients of acute STEMI with or without fibrinolytic therapy. Objectives This comparative study was designed to evaluate the outcomes of primary PCI in patients with acute STEMI in smokers and non-smokers. Clinical and angiographic profile of the two groups was also compared. Methods Over duration of two year, a total of 150 consecutive patients of acute STEMI eligible for primary PCI were enrolled and constituted the two groups [Smokers (n = 90), Non-smokers (n = 60)] of the study population. There was no difference in procedure in two groups. Results In the present study of acute STEMI, current smokers were about a decade younger than non-smokers (p value = 0.0002), majority were male (98.9% vs 56.6%) were male with a higher prevalence of hypertension and diabetes mellitus (61.67% vs 32.28% and 46.67% vs 14.44%, p = 0.001) respectively. Smokers tended to have higher thrombus burden (p = 0.06) but less multi vessel disease (p = 0.028). Thirty day and six month mortality was non-significantly higher in smokers 4.66% vs 1.33% (p = 0.261) and 5.33% vs 2.66% (p = NS) respectively. Rate of quitting smoking among smokers was 80.90% at 6 months. Conclusion The study documents that smokers with acute STEMI have similar outcomes as compared to non smokers with higher thrombus burden and lesser non culprit artery involvement. Smokers present at much younger age emphasizing the role of smoking cessation for prevention of myocardial infarction.

Thermal modeling and simulation of a package-on-package embedded micro wafer level package (EMWLP) structure at the package and system-level

Abstract: In the embedded wafer-level packaging field, the embedded micro wafer level package (EMWLP) technology leverages on fan-out redistribution connections, keeping the reliance on wire-bonding and flip-chip bump connections to a minimum, thus streamlining the packaging process. As the embedded micro wafer level packaging (EMWLP) technology evolves to capitalize on package-on-package (POP) technology, this study's parametric thermal modeling focuses on analyzing the thermal impact of increased density in a low thermal conductivity packaging material. The package design in this work has the following specifications: the memory EMWLP (die size: 7×7×0.2mm) on logic EMWLP structure (die size : 8×8×0.2mm), sized 12×12×0.9mm in total. The POP structure, furthermore, incorporates through-mold-interconnects (TMI) in the bottom logic package to provide short electrical connection from the top package to the board level. The impact on multi-package thermal resistance is then studied as the following parameters vary: power dissipation (in both packages); mold conductivity; number of TMIs; number of solder ball connections; inclusion and size of an interpackage heatslug; inclusion and thermal conductivity of a top heatspreader. The thermal management of the dies are also studied based on the above measures and was found to accommodate under 4W of total POP power. Finally, simulation results for a general system-level thermal modeling of the EMWLP POP in a cellphone scenario are also conducted with passive thermal management solutions proposed.

In Vitro Propagation of Drynaria quercifolia (L.) J. Sm., a Medicinal Fern

Abstract: Drynaria quercifolia is a highly medicinal fern used traditionally all over the world to treat a variety of ailments. But due to indiscriminate collection and destruction of habitats, it is facing the verdict of being endangered. So it is high time to adopt the various conservation measures including its in vitro propagation. In order to conserve the species in situ, in vitro culture of spores of the plant was tried. The spores were found to germinate only on MS - Z4 medium (Full MS+1mg/L IAA+5mg/L Kinetin+20%CM+300mg/L CH). All other media used failed to produce prothallus. After inoculation, it took about 30 days to germinate. After development of the Prothallus and subsequent development sporophytes, the plantlets were transferred in different media but the best growth was observed in PNT-2 media (Full strength Parker and Thompson +5mg/L IAA+2mg/L Kinetin) where proliferation of vegetative fronds and rhizome were recorded.

I and i

Abstract: There is, I think, something ethereal about i —the square root of minus one. I remember first hearing about it at school. It seemed an odd beast at that time—an intruder hovering on the edge of reality. Usually familiarity dulls this sense of the bizarre, but in the case of i it was the reverse: over the years the sense of its surreal nature intensified. It seemed that it was impossible to write mathematics that described the real world in …

SPAdes, a new genome assembly algorithm and its applications to single-cell sequencing ( 7th Annual SFAF Meeting, 2012)

Abstract: The lion's share of bacteria in various environments cannot be cloned in the laboratory and thus cannot be sequenced using existing technologies. A major goal of single-cell genomics is to complement gene-centric metagenomic data with whole-genome assemblies of uncultivated organisms. Assembly of single-cell data is challenging because of highly non-uniform read coverage as well as elevated levels of sequencing errors and chimeric reads. We describe SPAdes, a new assembler for both single-cell and standard (multicell) assembly, and demonstrate that it improves on the recently released E+V-SC assembler (specialized for single-cell data) and on popular assemblers Velvet and SoapDeNovo (for multicell data). SPAdes generates single-cell assemblies, providing information about genomes of uncultivatable bacteria that vastly exceeds what may be obtained via traditional metagenomics studies. SPAdes is available online ( http://bioinf.spbau.ru/spades ). It is distributed as open source software.