There is, I think, something ethereal about i —the square root of minus one. I remember first hearing about it at school. It seemed an odd beast at that time—an intruder hovering on the edge of reality.

Usually familiarity dulls this sense of the bizarre, but in the case of i it was the reverse: over the years the sense of its surreal nature intensified. It seemed that it was impossible to write mathematics that described the real world in …

I and i

https://caltcm.memberclicks.net/assets/documents/acc_aha_chf_2013_guidelines.pdf

2013 ACCF/AHA Guideline for the Management of Heart Failure: A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines

The lion's share of bacteria in various environments cannot be cloned in the laboratory and thus cannot be sequenced using existing technologies. A major goal of single-cell genomics is to complement gene-centric metagenomic data with whole-genome assemblies of uncultivated organisms. Assembly of single-cell data is challenging because of highly non-uniform read coverage as well as elevated levels of sequencing errors and chimeric reads. We describe SPAdes, a new assembler for both single-cell and standard (multicell) assembly, and demonstrate that it improves on the recently released E+V-SC assembler (specialized for single-cell data) and on popular assemblers Velvet and SoapDeNovo (for multicell data). SPAdes generates single-cell assemblies, providing information about genomes of uncultivatable bacteria that vastly exceeds what may be obtained via traditional metagenomics studies. SPAdes is available online ( http://bioinf.spbau.ru/spades ). It is distributed as open source software.

SPAdes, a new genome assembly algorithm and its applications to single-cell sequencing ( 7th Annual SFAF Meeting, 2012)

Soil Chemical Analysis

Statistics for Spatial Data.

Apparatus and methods that adjust image data for show-through image information of an image on a front side of an image bearing substrate having image data on a back side and on an adjacent side of a backing substrate, e.g., the pages of a bound volume. Image data for a front side image, a back side image and an adjacent side image is obtained from an optical sensor that senses light reflected from the image bearing substrate. The image data is stored in a memory and is used to determine scanned density data and approximate absorbency data for the respective sides of the substrates. Show-through compensated density data for the front side image is computed by filtering the absorbency data for the back and adjacent side with a filter characteristic of the show-through characteristics of the image bearing substrate and subtracting this filtered absorbency data from the front side scanned density data. If required, the show-through compensated density data for the front, side image is converted into a show-through compensated reflectance image.

Show-through compensation apparatus and method

Diabetes mellitus is a heterogeneous disease characterized by altered cellular metabolism. So many traditional herbs are being used by diabetic patients to control this disease. The aim of this study was to investigate the effects of aqueous extract of aloe vera leaves on hypoglycemic activity and hepatoprotective effects after alloxan injection in Swiss albino mice. In this study, aqueous leaf extract of aloe vera was carried out. Diabetes was induced in mice by alloxan monohydrate at dose of 150 mg/kg body weight injected intraperitoneally. Also alloxanized induced mice were administered with 300 and 500 mg/kg body weight orally daily of extract for a period of 21 days. At the end of the administration period, the mice were anaesthesized and dissect for the collection of blood and liver tissues. In diabetic mice, the SGOT, SGPT and bilirubin level as well as serum glucose levels were significantly increased (p<0.05) in comparison with the control groups. Diabetic mice group treated by extract at the dose of 300 and 500 mg/kg body weight orally significantly (p<0.05) reduced and normalised these biochemical parameters compared with alloxan induced diabetic group. Histopathological study also did show adverse alternation in the morphological architecture of the liver tissue. The results suggested that aqueous extract of aloe vera leaves possesses protective effect against alloxan induced diabetic mice.

/pdf/hypoglycemic-and-hepatoprotective-effects-of-processed-aloe-21o8xg5ska.pdf

Hypoglycemic and Hepatoprotective Effects of Processed Aloe vera Gel in a Mice Model of Alloxan Induced Diabetes Mellitus

Halftoned separations of individual colorants, typically cyan, magenta, yellow, and black, are overlaid on a print substrate in typical color printing systems. Displacements between these separations, commonly referred to as "interseparation misregistra- tion", can cause objectionable color shifts in the prints. We study this misregistration-induced color shift for periodic clustered-dot half- tones using a spatiospectral model for the printed output that com- bines the Neugebauer model with a periodic lattice representation for the individual halftones. Using Fourier analysis in the framework of this model, we obtain an analytic characterization for the condi- tions for misregistration invariance in terms of colorant spectra, pe- riodicity of the individual separation halftones, dot shapes, and mis- registration displacements. We further exploit the framework in a hybrid analytical-numerical simulation that allows us to obtain quan- titative estimates of the color shifts due to misregistration, thereby providing a characterization for these shifts as a function of the op- tical dot gain, halftone periodicities, spot shapes, and intersepara- tion misregistration amounts. We present simulation results that demonstrate the impact of each of these parameters on the color shift and demonstrate qualitative agreement between our approxi- mation and experimental data. © 2008 SPIE and IS&T.

/pdf/misregistration-sensitivity-in-clustered-dot-color-halftones-r4gpzzt9rq.pdf

Misregistration sensitivity in clustered-dot color halftones

Covalent modification of proteins by ubiquitin (Ub) and ubiquitin-like modifiers (Ubls) regulates many cellular functions in eukaryotes. These modifications are likely to be associated with pathogenesis, growth, and development of many protozoan parasites but molecular details about this pathway are unavailable for most protozoa. This study presents an analysis of the Ub pathway in three members of the Entamoeba species. Using bioinformatics tools we have identified all Ub and Ubl genes along with their corresponding activating, conjugating, and ligating enzymes (E1, E2s, and E3s) in three Entamoeba species, Entamoeba histolytica, Entamoeba dispar, and Entamoeba invadens. Phylogenetic trees were established for the identified E2s and RING finger E3s using maximum-likelihood method to infer the relationship among these proteins. In silico co-domain analysis of RING finger E3s implicates these proteins in a variety of functions. Several known and putative regulatory motifs were identified in the upstream regions of RING finger domain containing E3 genes. All E2 and E3 genes were analyzed in genomic context in E. histolytica and E. dispar. Most E2s and E3s were in syntenic positions in the two genomes. Association of these genes with transposable elements (TEs) was compared between E. histolytica and E. dispar. A closer association was found between RING finger E3s with TEs in E. histolytica. In summary, our analyses suggests that the complexity of the Ub pathway in Entamoeba species is close to that observed in higher eukaryotes. This study provides important data for further understanding the role of Ub pathway in the biology of these organisms.

In silico analysis of ubiquitin/ubiquitin-like modifiers and their conjugating enzymes in Entamoeba species

FeCoNi ternary alloy nanowire arrays 32–106 nm in diameter were fabricated within nanoporous alumina membranes using 15 Vrms alternating current electrodeposition at frequencies of 50, 250, 500, 750, and 1000 Hz. The magnetic coercivity and hysteresis loop squareness-ratio (Mr/Ms) were studied as functions of electrolyte composition, nanowire diameter, and nanowire aspect ratio.

https://www.cambridge.org/core/services/aop-cambridge-core/content/view/S0884291400087793

Gaurav Sharma

Papers

Show-through compensation apparatus and method

Hypoglycemic and Hepatoprotective Effects of Processed Aloe vera Gel in a Mice Model of Alloxan Induced Diabetes Mellitus

Misregistration sensitivity in clustered-dot color halftones

In silico analysis of ubiquitin/ubiquitin-like modifiers and their conjugating enzymes in Entamoeba species

Synthesis, characterization, and magnetic properties of FeCoNi ternary alloy nanowire arrays