G
Gaurav Shukla
Researcher at Banaras Hindu University
Publications - 61
Citations - 619
Gaurav Shukla is an academic researcher from Banaras Hindu University. The author has contributed to research in topics: Annulation & Chemistry. The author has an hindex of 14, co-authored 45 publications receiving 492 citations.
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Catalyst-free one-pot four-component domino reactions in water–PEG-400: highly efficient and convergent approach to thiazoloquinoline scaffolds
Anugula Nagaraju,B. Janaki Ramulu,Gaurav Shukla,Abhijeet Srivastava,Girijesh Kumar Verma,Keshav Raghuvanshi,Maya Shankar Singh +6 more
TL;DR: In this paper, a cost-effective and eco-friendly straightforward synthesis of highly diversified thiazoloquinoline scaffolds is successfully achieved via one-pot four-component cascade reaction utilizing α-enolic dithioesters, cysteamine, aldehydes, and cyclic 1,3-diketones in water-PEG-400.
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Solvent-free sonochemical one-pot three-component synthesis of 2H-indazolo[2,1-b]phthalazine-1,6,11-triones and 1H-pyrazolo[1,2-b]phthalazine-5,10-diones
TL;DR: In this article, a rapid and efficient one-pot three-component protocol for the synthesis of 2 H -indazolo[2,1-b ]phthalazine-1,6,11-triones 4 and 1 H -pyrazolo[1,2- b ]phthalamide-5,10-diones 6 has been developed by domino coupling of phthalhydrazide, 1,3-diketones, and aldehydes under solvent-free conditions at 80°C as well as under solvent free ultrasound irradiation
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Eco-efficient, regioselective and rapid access to 4,5-disubstituted 1,2,3-thiadiazoles via [3 + 2] cycloaddition of α-enolicdithioesters with tosyl azide under solvent-free conditions
Maya Shankar Singh,Anugula Nagaraju,Girijesh Kumar Verma,Gaurav Shukla,Rajiv Kumar Verma,Abhijeet Srivastava,Keshav Raghuvanshi +6 more
TL;DR: The eco-compatibility, mild conditions, excellent yields, easy purification, and avoidance of expensive/toxic reagents are advantages of this protocol to access this medicinally privileged substructure.
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4-Dimethylamino Pyridine-Promoted One-Pot Three-Component Regioselective Synthesis of Highly Functionalized 4H-Thiopyrans via Heteroannulation of β-Oxodithioesters
TL;DR: Systematic optimization of reaction parameters identified that the three-component coupling (3CC) protocol is tolerant to a wide array of functionality providing densely functionalized 4H-thiopyrans in excellent yields.
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Metal- and Catalyst-Free, Formal [4 + 1] Annulation via Tandem C═O/C═S Functionalization: One-Pot Access to 3,5-Disubstituted/Annulated Isothiazoles.
TL;DR: An operationally simple and user-friendly new protocol for the synthesis of 3,5-disubstituted/annulated isothiazoles is devised utilizing β-ketodithioesters/β-ketothioamides and NH4OAc via C═O/C═S bond functionalization under metal- and catalyst-free conditions.