Gemma Piella

Bio: Gemma Piella is an academic researcher from Pompeu Fabra University. The author has contributed to research in topics: Computer science & Lifting scheme. The author has an hindex of 25, co-authored 143 publications receiving 4411 citations. Previous affiliations of Gemma Piella include Autonomous University of Barcelona & Polytechnic University of Catalonia.

Modified M-band synthesis filter bank for fractional scalability of images

Abstract: Subband image coding with classical wavelet transforms inherently provides dyadic scalability since the low-pass approximation band can be used as a half-sized version of the original image The multiresolution approach further provides scalability factors that are powers of two, but no other factors can be easily reached On the other hand, a hierarchical scheme based on M-bandtransforms will lead only to scalability factors that are powers of M In this letter, we present how an M-band synthesis filter bank can be modified in order to directly reconstruct an output image of a resolution reduced by a factor M/P, where P is an integer lower than M As the analysis filter bank is not modified, this technique allows the design of subband decoding schemes that support fractional scalability With this feature, the same compressed bitstream can be directly decoded by different receivers at several resolutions, depending on their computational and bandwith capabilities

Revealing heterogeneity of brain imaging phenotypes in Alzheimer's disease based on unsupervised clustering of blood marker profiles

Abstract: Alzheimer's disease (AD) affects millions of people and is a major rising problem in health care worldwide. Recent research suggests that AD could have different subtypes, presenting differences in how the disease develops. Characterizing those subtypes could be key to deepen the understanding of this complex disease. In this paper, we used a multivariate, non-supervised clustering method over blood-based markers to find subgroups of patients defined by distinctive blood marker profiles. Our analysis on ADNI database identified 4 possible subgroups, each with a different blood profile. More importantly, we show that subgroups with different profiles have a different relationship between brain phenotypes detected in magnetic resonance imaging and disease condition.

Nonlinear interaction between APOE ε4 allele load and age in the hippocampal surface of cognitively intact individuals

Abstract: The e4 allele of the gene Apolipoprotein E is the major genetic risk factor for Alzheimer's Disease. APOE e4 has been associated with changes in brain structure in cognitively impaired and unimpaired subjects, including atrophy of the hippocampus, which is one of the brain structures that is early affected by AD. In this work we analyzed the impact of APOE e4 gene dose and its association with age, on hippocampal shape assessed with multivariate surface analysis, in a e4-enriched cohort of n = 479 cognitively healthy individuals. Furthermore, we sought to replicate our findings on an independent dataset of n = 969 individuals covering the entire AD spectrum. We segmented the hippocampus of the subjects with a multi-atlas-based approach, obtaining high-dimensional meshes that can be analyzed in a multivariate way. We analyzed the effects of different factors including APOE, sex, and age (in both cohorts) as well as clinical diagnosis on the local 3D hippocampal surface changes. We found specific regions on the hippocampal surface where the effect is modulated by significant APOE e4 linear and quadratic interactions with age. We compared between APOE and diagnosis effects from both cohorts, finding similarities between APOE e4 and AD effects on specific regions, and suggesting that age may modulate the effect of APOE e4 and AD in a similar way.

La integración de la inteligencia artificial en el abordaje clínico del paciente: enfoque en la imagen cardiaca

Abstract: Resumen La imagen cardiaca es un componente crucial en el abordaje de los pacientes cardiacos, y como tal influye en multiples partes interrelacionadas del flujo de trabajo clinico: el contacto medico-paciente, la adquisicion de imagen, el preprocesamiento y posprocesamiento de imagenes, los informes de estudios, el diagnostico y el pronostico, las intervenciones medicas y, por ultimo, el desarrollo del conocimiento a traves de la investigacion clinica. La incesante infiltracion de la inteligencia artificial en cardiologia pone de manifiesto que, usada apropiadamente, influira y puede mejorar —a traves de la automatizacion, la estandarizacion y la integracion de datos— todos los componentes del flujo de trabajo clinico. El objetivo de esta revision es presentar una vision holistica de como se integra la inteligencia artificial en el abordaje clinico del paciente, con especial foco en la imagen cardiaca, pero aplicable a toda la gestion de informacion, y discutir las barreras actuales que aun deben superarse para su implementacion generalizada.

Global and Regional Changes in Cortical Development Assessed by MRI in Fetuses with Isolated Nonsevere Ventriculomegaly Correlate with Neonatal Neurobehavior.

Abstract: BACKGROUND AND PURPOSE: Fetuses with isolated nonsevere ventriculomegaly (INSVM) are at risk of presenting neurodevelopmental delay. However, the currently used clinical parameters are insufficient to select cases with high risk and determine whether subtle changes in brain development are present and might be a risk factor. The aim of this study was to perform a comprehensive evaluation of cortical development in INSVM by magnetic resonance (MR) imaging and assess its association with neonatal neurobehavior. MATERIALS AND METHODS: Thirty-two INSVM fetuses and 29 healthy controls between 26–28 weeks of gestation were evaluated using MR imaging. We compared sulci and fissure depth, cortical maturation grading of specific areas and sulci and volumes of different brain regions obtained from 3D brain reconstruction of cases and controls. Neonatal outcome was assessed by using the Neonatal Behavioral Assessment Scale at a mean of 4 ± 2 weeks after birth. RESULTS: Fetuses with INSVM showed less profound and underdeveloped sulcation, including the Sylvian fissure (mean depth: controls 16.8 ± 1.9 mm, versus INSVM 16.0 ± 1.6 mm; P = .01), and reduced global cortical grading (mean score: controls 42.9 ± 10.2 mm, versus INSVM: 37.8 ± 9.9 mm; P = .01). Fetuses with isolated nonsevere ventriculomegaly showed a mean global increase of gray matter volume (controls, 276.8 ± 46.0 ×10 mm3, versus INSVM 277.5 ± 49.3 ×10 mm3, P = .01), but decreased mean cortical volume in the frontal lobe (left: controls, 53.2 ± 8.8 ×10 mm3, versus INSVM 52.4 ± 5.4 ×10 mm3; P = CONCLUSIONS: INSVM fetuses showed differences in cortical development, including regions far from the lateral ventricles, that are associated with neonatal neurobehavior. These results suggest the possible use of these parameters to identify cases at higher risk of altered neurodevelopment.

The Design and Analysis of Experiments

Abstract: THE DESIGN AND ANALYSIS OF EXPERIMENTS. By Oscar Kempthorne. New York, John Wiley and Sons, Inc., 1952. 631 pp. $8.50. This book by a teacher of statistics (as well as a consultant for \"experimenters\") is a comprehensive study of the philosophical background for the statistical design of experiment. It is necessary to have some facility with algebraic notation and manipulation to be able to use the volume intelligently. The problems are presented from the theoretical point of view, without such practical examples as would be helpful for those not acquainted with mathematics. The mathematical justification for the techniques is given. As a somewhat advanced treatment of the design and analysis of experiments, this volume will be interesting and helpful for many who approach statistics theoretically as well as practically. With emphasis on the \"why,\" and with description given broadly, the author relates the subject matter to the general theory of statistics and to the general problem of experimental inference. MARGARET J. ROBERTSON

Mean squared error: Love it or leave it? A new look at Signal Fidelity Measures

Abstract: In this article, we have reviewed the reasons why we (collectively) want to love or leave the venerable (but perhaps hoary) MSE. We have also reviewed emerging alternative signal fidelity measures and discussed their potential application to a wide variety of problems. The message we are trying to send here is not that one should abandon use of the MSE nor to blindly switch to any other particular signal fidelity measure. Rather, we hope to make the point that there are powerful, easy-to-use, and easy-to-understand alternatives that might be deployed depending on the application environment and needs. While we expect (and indeed, hope) that the MSE will continue to be widely used as a signal fidelity measure, it is our greater desire to see more advanced signal fidelity measures being used, especially in applications where perceptual criteria might be relevant. Ideally, the performance of a new signal processing algorithm might be compared to other algorithms using several fidelity criteria. Lastly, we hope that we have given further motivation to the community to consider recent advanced signal fidelity measures as design criteria for optimizing signal processing algorithms and systems. It is in this direction that we believe that the greatest benefit eventually lies.

Data fusion

Abstract: The development of the Internet in recent years has made it possible and useful to access many different information systems anywhere in the world to obtain information. While there is much research on the integration of heterogeneous information systems, most commercial systems stop short of the actual integration of available data. Data fusion is the process of fusing multiple records representing the same real-world object into a single, consistent, and clean representation.This article places data fusion into the greater context of data integration, precisely defines the goals of data fusion, namely, complete, concise, and consistent data, and highlights the challenges of data fusion, namely, uncertain and conflicting data values. We give an overview and classification of different ways of fusing data and present several techniques based on standard and advanced operators of the relational algebra and SQL. Finally, the article features a comprehensive survey of data integration systems from academia and industry, showing if and how data fusion is performed in each.

Image Fusion With Guided Filtering

Abstract: A fast and effective image fusion method is proposed for creating a highly informative fused image through merging multiple images. The proposed method is based on a two-scale decomposition of an image into a base layer containing large scale variations in intensity, and a detail layer capturing small scale details. A novel guided filtering-based weighted average technique is proposed to make full use of spatial consistency for fusion of the base and detail layers. Experimental results demonstrate that the proposed method can obtain state-of-the-art performance for fusion of multispectral, multifocus, multimodal, and multiexposure images.