G
Genevieve K Phillips
Researcher at University of New Mexico
Publications - 16
Citations - 1943
Genevieve K Phillips is an academic researcher from University of New Mexico. The author has contributed to research in topics: Signal transduction & Autophosphorylation. The author has an hindex of 10, co-authored 16 publications receiving 1746 citations.
Papers
More filters
Journal ArticleDOI
The targeted delivery of multicomponent cargos to cancer cells by nanoporous particle-supported lipid bilayers
Carlee E. Ashley,Carlee E. Ashley,Eric C. Carnes,Genevieve K Phillips,David Patrick Padilla,Paul N. Durfee,Page A. Brown,Tracey N. Hanna,Juewen Liu,Juewen Liu,Brandy Phillips,Mark B. Carter,Nick J. Carroll,Xingmao Jiang,Darren R. Dunphy,Cheryl L. Willman,Dimiter N. Petsev,Deborah G. Evans,Atul N. Parikh,Bryce Chackerian,Walker Wharton,David S. Peabody,C. Jeffrey Brinker +22 more
TL;DR: P porous nanoparticle-supported lipid bilayers (protocells) that synergistically combine properties of liposomes and nanoporous particles are reported that allow a single protocell loaded with a drug cocktail to kill a drug-resistant HCC cell, representing a 106-fold improvement over comparable liposome.
Journal ArticleDOI
Cell-Specific Delivery of Diverse Cargos by Bacteriophage MS2 Virus-Like Particles
Carlee Erin Ashley,Eric C. Carnes,Genevieve K Phillips,Paul N. Durfee,Mekensey Buley,Christopher A. Lino,David Patrick Padilla,Brandy Phillips,Mark B. Carter,Cheryl L. Willman,C. Jeffrey Brinker,Jerri C. Caldeira,Bryce Chackerian,Walker Wharton,David S. Peabody +14 more
TL;DR: The results demonstrate that MS2 VLPs, because of their tolerance of multivalent peptide display and their ability to specifically encapsidate a variety of chemically disparate cargos, induce selective cytotoxicity of cancer in vitro and represent a significant improvement in the characteristics of VLP-based delivery systems.
Journal ArticleDOI
Delivery of small interfering RNA by peptide-targeted mesoporous silica nanoparticle-supported lipid bilayers
Carlee E. Ashley,Carlee E. Ashley,Eric C. Carnes,Katharine E. Epler,David Patrick Padilla,Genevieve K Phillips,Robert Castillo,Dan C. Wilkinson,Brian S. Wilkinson,Cameron Burgard,Robin M. Kalinich,Jason L. Townson,Bryce Chackerian,Cheryl L. Willman,David S. Peabody,Walker Wharton,C. Jeffrey Brinker +16 more
TL;DR: It is reported that mesoporous silica nanoparticle-supported lipid bilayers (or "protocells") exhibit multiple properties that overcome many of the limitations of existing delivery platforms.
Journal ArticleDOI
Erratum: The targeted delivery of multicomponent cargos to cancer cells by nanoporous particle-supported lipid bilayers (Nature Materials (2011) 10 (389-397))
Carlee Erin Ashley,Eric C. Carnes,Genevieve K Phillips,David Patrick Padilla,Paul N. Durfee,Page A. Brown,Tracey N. Hanna,Juewen Liu,Brandy Phillips,Mark B. Carter,Nick J. Carroll,Xingmao Jiang,Darren R. Dunphy,Cheryl L. Willman,Dimiter N. Petsev,Deborah G. Evans,Atul N. Parikh,Bryce Chackerian,Walker Wharton,David S. Peabody,C. Jeffrey Brinker +20 more
Journal ArticleDOI
Characterization of a Cdc42 protein inhibitor and its use as a molecular probe.
Lin Hong,S. Ray Kenney,Genevieve K Phillips,Denise S. Simpson,Chad E. Schroeder,Julica Nöth,Elsa Romero,Scarlett Swanson,Anna Waller,J. Jacob Strouse,Mark B. Carter,Alexandre Chigaev,Oleg Ursu,Tudor I. Oprea,Brian Hjelle,Jennifer E. Golden,Jeffrey Aubé,Laurie G. Hudson,Tione Buranda,Larry A. Sklar,Angela Wandinger-Ness +20 more
TL;DR: The characterization of a novel Cdc42-selective allosteric inhibitor and a related analog are presented, the use of which will facilitate drug development targeting CDC42-related diseases and molecular pathway studies that involve GTPases.