Genís Parra

TL;DR: The results of an international collaboration to produce a high-quality draft sequence of the mouse genome are reported and an initial comparative analysis of the Mouse and human genomes is presented, describing some of the insights that can be gleaned from the two sequences.

TL;DR: A draft genome sequence of the red jungle fowl, Gallus gallus, provides a new perspective on vertebrate genome evolution, while also improving the annotation of mammalian genomes.

TL;DR: This study reports a computational method, CEGMA (Core Eukaryotic Genes Mapping Approach), for building a highly reliable set of gene annotations in the absence of experimental data, and defines a set of conserved protein families that occur in a wide range of eukaryotes and presents a mapping procedure that accurately identifies their exon-intron structures in a novel genomic sequence.

TL;DR: Genome analysis provides a greatly improved fish gene catalogue, including identifying key genes previously thought to be absent in fish, and reconstructs much of the evolutionary history of ancient and recent chromosome rearrangements leading to the modern human karyotype.

TL;DR: The results demonstrate that MAKER provides a simple and effective means to convert a genome sequence into a community-accessible genome database, and should prove especially useful for emerging model organism genome projects for which extensive bioinformatics resources may not be readily available.