G
George C. Brainard
Researcher at Thomas Jefferson University
Publications - 110
Citations - 13082
George C. Brainard is an academic researcher from Thomas Jefferson University. The author has contributed to research in topics: Melatonin & Circadian rhythm. The author has an hindex of 50, co-authored 102 publications receiving 11506 citations. Previous affiliations of George C. Brainard include Brigham and Women's Hospital & Washington University in St. Louis.
Papers
More filters
Journal ArticleDOI
Action Spectrum for Melatonin Regulation in Humans: Evidence for a Novel Circadian Photoreceptor
George C. Brainard,John P. Hanifin,Jeffrey M. Greeson,Brenda Byrne,Gena Glickman,Edward Gerner,Mark D. Rollag +6 more
TL;DR: The results suggest that, in humans, a single photopigment may be primarily responsible for melatonin suppression, and its peak absorbance appears to be distinct from that of rod and cone cellphotopigments for vision.
Journal ArticleDOI
The Devil is in the Third Year: A Longitudinal Study of Erosion of Empathy in Medical School
Mohammadreza Hojat,Michael J. Vergare,Kaye Maxwell,George C. Brainard,Steven K. Herrine,Gerald A. Isenberg,John Veloski,Joseph S. Gonnella +7 more
TL;DR: It is concluded that a significant decline in empathy occurs during the third year of medical school, and it is ironic that the erosion of empathy occurs when the curriculum is shifting toward patient-care activities; this is when empathy is most essential.
Journal ArticleDOI
Measuring and using light in the melanopsin age
Robert J. Lucas,Stuart N. Peirson,David M. Berson,Timothy M. Brown,Howard M. Cooper,Charles A. Czeisler,Mariana G. Figueiro,Paul D. Gamlin,Steven W. Lockley,John O’Hagan,Luke L. A. Price,Ignacio Provencio,Debra J. Skene,George C. Brainard +13 more
TL;DR: A new light-measurement strategy taking account of the complex photoreceptive inputs to these non-visual responses is proposed for use by researchers, and simple suggestions for artificial/architectural lighting are provided for regulatory authorities, lighting manufacturers, designers, and engineers.
Journal ArticleDOI
High Sensitivity of the Human Circadian Melatonin Rhythm to Resetting by Short Wavelength Light
TL;DR: It is reported here that the circadian resetting response in humans, as measured by the pineal melatonin rhythm, is also wavelength dependent, and photopic lux, the standard unit of illuminance, is inappropriate when quantifying the photic drive required to reset the human circadian pacemaker.
Journal ArticleDOI
Short-wavelength sensitivity for the direct effects of light on alertness, vigilance, and the waking electroencephalogram in humans
Steven W. Lockley,Steven W. Lockley,Erin E. Evans,Frank A.J.L. Scheer,Frank A.J.L. Scheer,George C. Brainard,Charles A. Czeisler,Charles A. Czeisler,Daniel Aeschbach,Daniel Aeschbach +9 more
TL;DR: The frequency-specific changes in the waking EEG indicate that short-wavelength light is a powerful agent that immediately attenuates the negative effects of both homeostatic sleep pressure and the circadian drive for sleep on alertness, performance, and the ability to sustain attention.