G
George Davey Smith
Researcher at University of Bristol
Publications - 2646
Citations - 294406
George Davey Smith is an academic researcher from University of Bristol. The author has contributed to research in topics: Population & Mendelian randomization. The author has an hindex of 224, co-authored 2540 publications receiving 248373 citations. Previous affiliations of George Davey Smith include Keele University & Western Infirmary.
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Journal ArticleDOI
Plasma urate concentration and risk of coronary heart disease: a Mendelian randomisation analysis.
Jon White,Reecha Sofat,Gibran Hemani,Tina Shah,Jorgen Engmann,Caroline Dale,Sonia Shah,Felix A. Kruger,Claudia Giambartolomei,Daniel I. Swerdlow,Tom Palmer,Stela McLachlan,Claudia Langenberg,Claudia Langenberg,Delilah Zabaneh,Ruth C. Lovering,Alana Cavadino,Barbara J. Jefferis,Chris Finan,Andrew Wong,Antoinette Amuzu,Ken K. Ong,Tom R. Gaunt,Helen R. Warren,Teri Louise Davies,Fotios Drenos,Fotios Drenos,Jackie A. Cooper,Shah Ebrahim,Debbie A Lawlor,Philippa J. Talmud,Steve E. Humphries,Christine Power,Elina Hyppönen,Elina Hyppönen,Marcus Richards,Rebecca Hardy,Diana Kuh,Nicholas J. Wareham,Yoav Ben-Shlomo,Ian N. M. Day,Peter H. Whincup,Richard W Morris,Mark W. J. Strachan,Jacqueline F. Price,Meena Kumari,Mika Kivimäki,Vincent Plagnol,John C. Whittaker,George Davey Smith,Frank Dudbridge,Juan P. Casas,Juan P. Casas,Michael V. Holmes,Michael V. Holmes,Aroon D. Hingorani +55 more
TL;DR: Conventional and multivariate Mendelian randomisation analysis implicates a causal role for urate in the development of coronary heart disease, but these estimates might be inflated by hidden pleiotropy.
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Approaches for drawing causal inferences from epidemiological birth cohorts: a review.
TL;DR: A suite of methods has been developed in recent years to minimise problems afflicting observational epidemiology, to strengthen causal inference and to provide greater insights into modifiable intra-uterine and early life risk factors, to be applied in the context of birth cohorts and extended along with the development of birth cohort consortia and expansion of "omic" technologies.
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Genome Wide Association Identifies Common Variants at the SERPINA6/SERPINA1 Locus Influencing Plasma Cortisol and Corticosteroid Binding Globulin
Jennifer L. Bolton,Caroline Hayward,Nese Direk,John G. Lewis,Geoffrey L. Hammond,Lesley A. Hill,Anna Anderson,Jennifer E. Huffman,James F. Wilson,Harry Campbell,Igor Rudan,Alan F. Wright,Nicholas D. Hastie,Sarah H. Wild,Fleur P. Velders,Albert Hofman,André G. Uitterlinden,Jari Lahti,Katri Räikkönen,Eero Kajantie,Elisabeth Widen,Aarno Palotie,Johan G. Eriksson,Marika Kaakinen,Marjo-Riitta Järvelin,Nicholas J. Timpson,George Davey Smith,Susan M. Ring,David M. Evans,Beate St Pourcain,Toshiko Tanaka,Yuri Milaneschi,Yuri Milaneschi,Stefania Bandinelli,Luigi Ferrucci,Pim van der Harst,Judith G. M. Rosmalen,Stephen J. L. Bakker,Niek Verweij,Robin P. F. Dullaart,Anubha Mahajan,Cecilia M. Lindgren,Andrew P. Morris,Lars Lind,Erik Ingelsson,Laura N. Anderson,Craig E. Pennell,Stephen J. Lye,Stephen G. Matthews,Joel Eriksson,Dan Mellström,Claes Ohlsson,Jackie F. Price,Mark W. J. Strachan,Rebecca M. Reynolds,Henning Tiemeier,Brian R. Walker +56 more
TL;DR: Findings reveal a novel common genetic source of variation in binding of cortisol by CBG, and reinforce the key role of CBG in determining plasma cortisol levels, and may contribute to cortisol-associated degenerative diseases.
Journal ArticleDOI
Nanoscale characterisation of grain boundary oxidation in cold-worked stainless steels
Karen Kruska,Sergio Lozano-Perez,David W. Saxey,Takumi Terachi,Takuyo Yamada,George Davey Smith +5 more
TL;DR: In this paper, atom-probe tomography was employed to characterise specimens containing the oxidised part of a grain boundary from a 304 stainless steel coupon specimen exposed to simulated PWR primary water.
Journal ArticleDOI
Socioeconomic disparities in trajectories of adiposity across childhood
TL;DR: The results imply that interventions to prevent inequalities in childhood obesity should begin in pre-school years, with daughters of more educated women being less adipose.