G
George Davey Smith
Researcher at University of Bristol
Publications - 2646
Citations - 294406
George Davey Smith is an academic researcher from University of Bristol. The author has contributed to research in topics: Population & Mendelian randomization. The author has an hindex of 224, co-authored 2540 publications receiving 248373 citations. Previous affiliations of George Davey Smith include Keele University & Western Infirmary.
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Journal ArticleDOI
Strong inverse association between height and suicide in a large cohort of Swedish men: evidence of early life origins of suicidal behavior?
TL;DR: The strong inverse association between height and suicide may signify the importance of childhood exposure in the etiology of adult mental disorder or reflect stigmatization or discrimination encountered by short men in their adult lives.
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Promotion of condom use in a high-risk setting in Nicaragua: a randomised controlled trial
Matthias Egger,Matthias Egger,J Pauw,Athanasios Lopatatzidis,Danilo Medrano,Fred Paccaud,George Davey Smith +6 more
TL;DR: Making condoms available in rooms is the most effective strategy to increase condom use, whereas use of health-education material was ineffective, having important implications for HIV-prevention policies.
Journal ArticleDOI
Analysis of the individual and aggregate genetic contributions of previously identified serine peptidase inhibitor Kazal type 5 (SPINK5), kallikrein-related peptidase 7 (KLK7), and filaggrin (FLG) polymorphisms to eczema risk.
Stephan Weidinger,Hansjoerg Baurecht,Stefan Wagenpfeil,John Henderson,Natalija Novak,Aileen Sandilands,Huijia Chen,Elke Rodriguez,Grainne M. O'Regan,Rosemarie Watson,Haihui Liao,Yiwei Zhao,Jonathan Barker,Michael H. Allen,Nick J. Reynolds,SJ Meggitt,Kate Northstone,George Davey Smith,Carolin Strobl,Caroline Stahl,Thomas Kneib,Norman Klopp,Thomas Bieber,Heidrun Behrendt,Colin N. A. Palmer,H.-Erich Wichmann,Johannes Ring,Thomas Illig,W.H. Irwin McLean,Alan D. Irvine,Alan D. Irvine +30 more
TL;DR: The SPINK5 420LysSer mutation confers a risk of ecZema when maternally inherited but is not a major eczema risk factor, and the KLK7 insertion appears to confer no risk of Eczema.
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Shared genetic influences between attention-deficit/hyperactivity disorder (ADHD) traits in children and clinical ADHD.
Evie Stergiakouli,Joanna Martin,Marian L. Hamshere,Kate Langley,David M. Evans,David M. Evans,Beate St Pourcain,Nicholas J. Timpson,Michael John Owen,Michael Conlon O'Donovan,Anita Thapar,George Davey Smith +11 more
TL;DR: Evidence is provided that shared genetic factors contribute to both behavioral traits in the general population and psychiatric disorders at least in the case of ADHD, highlighting the relevance of additive genetic variance in ADHD.
Posted ContentDOI
Within-family studies for Mendelian randomization: avoiding dynastic, assortative mating, and population stratification biases
Ben Michael Brumpton,Ben Michael Brumpton,Eleanor Sanderson,Fernando Pires Hartwig,Fernando Pires Hartwig,Sean Harrison,Gunnhild Åberge Vie,Yoonsu Cho,Laura D Howe,Amanda Hughes,Dorret I. Boomsma,Alexandra Havdahl,Alexandra Havdahl,John L. Hopper,Michael C. Neale,Michel G. Nivard,Nancy L. Pedersen,Chandra A. Reynolds,Elliot M. Tucker-Drob,Andrew D. Grotzinger,Laurence J. Howe,Tim T Morris,Shuai Li,Shuai Li,Wei-Min Chen,Johan Håkon Bjørngaard,Kristian Hveem,Cristen J. Willer,David M. Evans,David M. Evans,Jaakko Kaprio,George Davey Smith,Bjørn Olav Åsvold,Gibran Hemani,Neil M Davies +34 more
TL;DR: Differences between population-based and within-family based MR estimates are found, indicating the importance of controlling for family effects and population structure in Mendelian randomization studies.