G
George Davey Smith
Researcher at University of Bristol
Publications - 2646
Citations - 294406
George Davey Smith is an academic researcher from University of Bristol. The author has contributed to research in topics: Population & Mendelian randomization. The author has an hindex of 224, co-authored 2540 publications receiving 248373 citations. Previous affiliations of George Davey Smith include Keele University & Western Infirmary.
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Health effects of anticipation of job change and non-employment: longitudinal data from the Whitehall II study
TL;DR: The application of a longitudinal design, allowing the same individuals to be followed from job security into anticipation, provides more robust evidence than has previously been available that anticipation of job loss affects health even before employment status has changed.
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Alanine Aminotransferase, γ-Glutamyltransferase, and Incident Diabetes: The British Women's Heart and Health Study and meta-analysis
TL;DR: Findings are consistent with the role of liver fat in diabetes pathogenesis, and suggest that GGT may be a better diabetes predictor than ALT, but additional studies with directly determined liver fat content, AlT, and GGT are needed to confirm this finding.
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Is the association between childhood socioeconomic circumstances and cause-specific mortality established? Update of a systematic review
TL;DR: The new studies confirmed that mortality risk for all causes was higher among those who experienced poorer socioeconomic circumstances during childhood and show that this association persists among younger birth cohorts, despite temporal general improvements in childhood conditions across successive birth cohorts.
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Two-sample Mendelian randomization: avoiding the downsides of a powerful, widely applicable but potentially fallible technique.
TL;DR: Two-sample Mendelian randomization: avoiding the downsides of a powerful, widely applicable but potentially fallible technique
Journal ArticleDOI
A genome-wide association meta-analysis identifies new childhood obesity loci
Jonathan P. Bradfield,H R Taal,Nicholas J. Timpson,André Scherag,C. Lecoeur,Nicole M. Warrington,Elina Hyppönen,Claus Holst,Beatriz Valcarcel,Elisabeth Thiering,Rany M. Salem,Fredrick R. Schumacher,Diana L. Cousminer,Pma Sleiman,Jianhua Zhao,Robert I. Berkowitz,Karani Santhanakrishnan Vimaleswaran,Ivonne Jarick,Craig E. Pennell,David M. Evans,B. St Pourcain,Diane J. Berry,Dennis O. Mook-Kanamori,Albert Hofman,Fernando Rivadeneira,André G. Uitterlinden,C M van Duijn,Rjp van der Valk,J. C. de Jongste,D. S. Postma,Dorret I. Boomsma,W. J. Gauderman,Mohamed T. Hassanein,Cecilia M. Lindgren,Reedik Mägi,Reedik Mägi,Cag Boreham,Charlotte E. Neville,Luis A. Moreno,Paul Elliott,A Pouta,A.-L. Hartikainen,Mingyao Li,Olli T. Raitakari,Terho Lehtimäki,Johan G. Eriksson,Aarno Palotie,Jean Dallongeville,Shikta Das,Panagiotis Deloukas,George McMahon,Susan M. Ring,John P. Kemp,Jessica L. Buxton,Aif Blakemore,Mariona Bustamante,Mònica Guxens,Joel N. Hirschhorn,Matthew W. Gillman,Eskil Kreiner-Møller,Hans Bisgaard,Frank D. Gilliland,Joachim Heinrich,Eleanor Wheeler,Inês Barroso,Inês Barroso,Stephen O'Rahilly,Aline Meirhaeghe,Tia Sorensen,Chris Power,Lyle J. Palmer,Anke Hinney,E. Widen,I. S. Farooqi,Mark I. McCarthy,Philippe Froguel,Philippe Froguel,David Meyre,David Meyre,Johannes Hebebrand,M-R Jarvelin,Vwv Jaddoe,George Davey Smith,Hakon Hakonarson,Sfa Grant +84 more
TL;DR: A North American, Australian and European collaborative meta-analysis of 14 studies consisting of 5,530 cases and 8,318 controls of European ancestry observed two loci that yielded genome-wide significant combined P values near OLFM4 at 13q14 and within HOXB5 at 17q21, which yielded directionally consistent associations.