G
George Davey Smith
Researcher at University of Bristol
Publications - 2646
Citations - 294406
George Davey Smith is an academic researcher from University of Bristol. The author has contributed to research in topics: Population & Mendelian randomization. The author has an hindex of 224, co-authored 2540 publications receiving 248373 citations. Previous affiliations of George Davey Smith include Keele University & Western Infirmary.
Papers
More filters
Journal ArticleDOI
The fat mass–and obesity-associated locus and dietary intake in children
Nicholas J. Timpson,Pauline M Emmett,Timothy M. Frayling,Imogen Rogers,Andrew T. Hattersley,Mark I. McCarthy,George Davey Smith +6 more
TL;DR: In this paper, a region of chromosome 16 containing the fat mass-and obesity-associated gene (FTO) is reproducibly associated with fat mass and body mass index (BMI), risk of obesity and adiposity.
Journal ArticleDOI
Field-ion specimen preparation using focused ion-beam milling
D.J. Larson,D T Foord,A. K. Petford-Long,H Liew,Mark G. Blamire,Alfred Cerezo,George Davey Smith +6 more
TL;DR: In this paper, the authors used focused ion-beam milling in either a simple cutting mode or by application of an annular-shaped ion-milling pattern to produce a smaller shank angle and a sharper apex radius.
Journal ArticleDOI
A road map for efficient and reliable human genome epidemiology.
John P. A. Ioannidis,John P. A. Ioannidis,Marta Gwinn,Julian Little,Julian P T Higgins,Jonine L. Bernstein,Paolo Boffetta,Melissa L. Bondy,Molly S. Bray,Paul Brenchley,Patricia A. Buffler,Juan P. Casas,Anand P. Chokkalingam,John Danesh,George Davey Smith,Siobhan M. Dolan,Ross Duncan,Nelleke A. Gruis,Patricia Hartge,Mia Hashibe,David J. Hunter,Marjo-Riitta Järvelin,Marjo-Riitta Järvelin,Beatrice Malmer,Demetrius M. Maraganore,Julia Newton-Bishop,Thomas R. O'Brien,Gloria M. Petersen,Elio Riboli,Georgia Salanti,Georgia Salanti,Daniela Seminara,Liam Smeeth,Emanuela Taioli,Nic Timpson,André G. Uitterlinden,Paolo Vineis,Nicholas J. Wareham,Deborah M. Winn,Ron Zimmern,Muin J. Khoury +40 more
TL;DR: Networks of investigators have begun sharing best practices, tools and methods for analysis of associations between genetic variation and common diseases, and a Network of Investigator Networks has been set up to drive the process.
Journal ArticleDOI
Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index.
Janine F. Felix,Jonathan P. Bradfield,Claire Monnereau,Ralf J. P. van der Valk,Evie Stergiakouli,Alessandra Chesi,Romy Gaillard,Bjarke Feenstra,Elisabeth Thiering,Eskil Kreiner-Møller,Anubha Mahajan,Pitkänen Niina Pitkänen,Pitkänen Niina Pitkänen,Raimo Joro,Alana Cavadino,Alana Cavadino,Ville Huikari,Steve Franks,Maria M. Groen-Blokhuis,Diana L. Cousminer,Julie A. Marsh,Terho Lehtimäki,John A. Curtin,Jesús Vioque,Tarunveer S. Ahluwalia,Tarunveer S. Ahluwalia,Ronny Myhre,Thomas S. Price,Vilor-Tejedor Natalia Vilor-Tejedor,Loic Yengo,Niels Grarup,Ioanna Ntalla,Ioanna Ntalla,Wei Ang,Mustafa Atalay,Hans Bisgaard,Alexandra I. F. Blakemore,Amélie Bonnefond,Lisbeth Carstensen,Johan G. Eriksson,Claudia Flexeder,Lude Franke,Frank Geller,Mandy Geserick,Anna-Liisa Hartikainen,Claire M. A. Haworth,Joel N. Hirschhorn,Joel N. Hirschhorn,Albert Hofman,Jens-Christian Holm,Momoko Horikoshi,Jouke-Jan Hottenga,Jinyan Huang,Haja N. Kadarmideen,Mika Kähönen,Wieland Kiess,Hanna Maaria Lakka,Timo A. Lakka,Alexandra M. Lewin,Liming Liang,Leo-Pekka Lyytikäinen,Baoshan Ma,Per Magnus,Shana E. McCormack,George McMahon,Frank D. Mentch,Christel M. Middeldorp,Clare S. Murray,Katja Pahkala,Tune H. Pers,Tune H. Pers,Roland Pfäffle,Dirkje S. Postma,Christine Power,Angela Simpson,Verena Sengpiel,Carla M. T. Tiesler,Maties Torrent,André G. Uitterlinden,Joyce B. J. van Meurs,Rebecca K. Vinding,Johannes Waage,Jane Wardle,Eleftheria Zeggini,Babette S. Zemel,George Dedoussis,Oluf Pedersen,Philippe Froguel,Jordi Sunyer,Robert Plomin,Bo Jacobsson,Bo Jacobsson,Torben Hansen,Juan R. González,Adnan Custovic,Olli T. Raitakari,Craig E. Pennell,Widén Elisabeth Widén,Dorret I. Boomsma,Gerard H. Koppelman,Sylvain Sebert,Marjo-Riitta Järvelin,Elina Hyppönen,Mark I. McCarthy,Mark I. McCarthy,Virpi Lindi,Niinikoski Harri,Antje Körner,Klaus Bønnelykke,Joachim Heinrich,Mads Melbye,Mads Melbye,Fernando Rivadeneira,Hakon Hakonarson,Hakon Hakonarson,Susan M. Ring,George Davey Smith,Thorkild I. A. Sørensen,Thorkild I. A. Sørensen,Nicholas J. Timpson,Struan F.A. Grant,Vincent W. V. Jaddoe,Heidi J. Kalkwarf,Joan M. Lappe,Vicente Gilsanz,Sharon E. Oberfield,John A. Shepherd,Andrea Kelly +127 more
TL;DR: A meta-analysis of genome-wide association studies of childhood body mass index, using sex- and age-adjusted standard deviation scores, identifies three novel loci that likely represent age-related differences in strength of the associations with bodymass index.
Genetic Risk for Autism Spectrum Disorders and Neuropsychiatric Variation in the General Population
Elise B. Robinson,Beate St Pourcain,Beate St Pourcain,Verneri Anttila,Brendan Bulik-Sullivan,Jack A. Kosmicki,Kaitlin E. Samocha,Julian Maller,David Skuse,Jakob Grove,Preben Bo Mortensen,Anders D. Børglum,Benjamin M. Neale,Angelica Ronald,George Davey Smith,Mark J. Daly +15 more
TL;DR: The authors found genome-wide genetic links between autism spectrum disorders and typical variation in social behavior and adaptive functioning through LD score correlation and de novo variant analysis, indicating that multiple types of genetic risk for ASDs influence a continuum of behavioral and developmental traits, the severe tail of which can result in diagnosis with an ASD or other neuropsychiatric disorder.