G
George Davey Smith
Researcher at University of Bristol
Publications - 2646
Citations - 294406
George Davey Smith is an academic researcher from University of Bristol. The author has contributed to research in topics: Population & Mendelian randomization. The author has an hindex of 224, co-authored 2540 publications receiving 248373 citations. Previous affiliations of George Davey Smith include Keele University & Western Infirmary.
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Journal ArticleDOI
Uses and abuses of meta-analysis.
TL;DR: It is argued that meta-analysis should be performed only within the framework of systematic reviews--that is, reviews prepared using a systematic approach to minimise bias and address the combinability of studies.
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Maternal pre-pregnancy BMI and gestational weight gain, offspring DNA methylation and later offspring adiposity: findings from the Avon Longitudinal Study of Parents and Children
Gemma C Sharp,Debbie A Lawlor,Rebecca C Richmond,Abigail Fraser,Andrew J Simpkin,Matthew Suderman,Hashem A. Shihab,Oliver Lyttleton,Wendy L. McArdle,Susan M. Ring,Tom R. Gaunt,George Davey Smith,Caroline L Relton +12 more
TL;DR: The data suggest that both maternal obesity and, to a larger degree, underweight affect the neonatal epigenome via an intrauterine mechanism, but weight gain during pregnancy has little effect.
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Patterns, distribution, and determinants of under- and overnutrition: a population-based study of women in India
TL;DR: Undernutrition and over malnutrition are epidemics of the impoverished and the affluent, respectively, in India, and this association is consistent at the individual and ecologic levels, and policies should focus on the complex patterns of social distribution of both under- and overnutrition in the Indian context.
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Altered muscle insulin sensitivity in the male offspring of protein-malnourished rats
TL;DR: The results suggest that programming of muscle insulin sensitivity can occur during fetal life, and insulin increased the GLUT-4 content of control plasma membranes but had no effect in low-protein animals.
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Genetic evidence for causal relationships between maternal obesity-related traits and birth weight
Jessica Tyrrell,Jessica Tyrrell,Rebecca C Richmond,Rebecca C Richmond,Tom Palmer,Tom Palmer,Bjarke Feenstra,Janani Rangarajan,Sarah Metrustry,Alana Cavadino,Alana Cavadino,Lavinia Paternoster,Loren L. Armstrong,N. Maneka G. De Silva,Andrew R. Wood,Momoko Horikoshi,Momoko Horikoshi,Frank Geller,Ronny Myhre,Jonathan P. Bradfield,Eskil Kreiner-Møller,Ville Huikari,Jodie N. Painter,Jouke-Jan Hottenga,Jouke-Jan Hottenga,Catherine Allard,Catherine Allard,Diane J. Berry,Luigi Bouchard,Luigi Bouchard,Shikta Das,David M. Evans,David M. Evans,Hakon Hakonarson,Hakon Hakonarson,M. Geoffrey Hayes,Jani Heikkinen,Albert Hofman,Albert Hofman,Bridget A. Knight,Penelope A. Lind,Mark I. McCarthy,Mark I. McCarthy,Mark I. McCarthy,George McMahon,Sarah E. Medland,Mads Melbye,Mads Melbye,Andrew P. Morris,Andrew P. Morris,Michael Nodzenski,Christoph Reichetzeder,Christoph Reichetzeder,Susan M. Ring,Sylvain Sebert,Sylvain Sebert,Verena Sengpiel,Thorkild I. A. Sørensen,Thorkild I. A. Sørensen,Gonneke Willemsen,Gonneke Willemsen,Eco J. C. de Geus,Eco J. C. de Geus,Nicholas G. Martin,Tim D. Spector,Christine Power,Marjo-Riitta Järvelin,Hans Bisgaard,Struan F.A. Grant,Struan F.A. Grant,Ellen A. Nohr,Vincent W. V. Jaddoe,Bo Jacobsson,Bo Jacobsson,Jeff Murray,Berthold Hocher,Berthold Hocher,Andrew T. Hattersley,Denise M. Scholtens,George Davey Smith,Marie-France Hivert,Marie-France Hivert,Janine F. Felix,Elina Hyppönen,Elina Hyppönen,William L. Lowe,Timothy M. Frayling,Debbie A Lawlor,Rachel M. Freathy,Rachel M. Freathy +89 more
TL;DR: For BMI and fasting glucose, genetic associations were consistent with the observational associations, but for systolic blood pressure, the genetic and observational associations were in opposite directions.