G
George Davey Smith
Researcher at University of Bristol
Publications - 2646
Citations - 294406
George Davey Smith is an academic researcher from University of Bristol. The author has contributed to research in topics: Population & Mendelian randomization. The author has an hindex of 224, co-authored 2540 publications receiving 248373 citations. Previous affiliations of George Davey Smith include Keele University & Western Infirmary.
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Journal ArticleDOI
Does Greater Adiposity Increase Blood Pressure and Hypertension Risk?: Mendelian Randomization Using the FTO/MC4R Genotype
Nicholas J. Timpson,Roger M. Harbord,George Davey Smith,Jeppe Zacho,Anne Tybjærg-Hansen,Børge G. Nordestgaard +5 more
TL;DR: Observed associations are large and illustrate the considerable benefits in terms of reductions in blood pressure–related morbidity that could be achieved through a reduction in body mass index.
Journal ArticleDOI
Why are the Japanese living longer
TL;DR: A comparative analysis of life expectancy in the United Kingdom and Japan is presented using data from official sources, finding no clear explanation for the higher life expectancy for both sexes in Japan.
Journal ArticleDOI
The Role of Adiposity in Cardiometabolic Traits: A Mendelian Randomization Analysis
Tove Fall,Sara Hägg,Sara Hägg,Reedik Mägi,Reedik Mägi,Alexander Ploner,Krista Fischer,Momoko Horikoshi,Momoko Horikoshi,Antti-Pekka Sarin,Gudmar Thorleifsson,Claes Ladenvall,Mart Kals,Maris Kuningas,Harmen H.M. Draisma,Janina S. Ried,Natalie R. van Zuydam,Ville Huikari,Massimo Mangino,Emily Sonestedt,Beben Benyamin,Beben Benyamin,Christopher P. Nelson,Christopher P. Nelson,Natalia V. Rivera,Kati Kristiansson,Huei-Yi Shen,Huei-Yi Shen,Aki S. Havulinna,Abbas Dehghan,Louise A. Donnelly,Marika Kaakinen,Marja-Liisa Nuotio,Neil Robertson,Neil Robertson,Renée F.A.G. de Bruijn,M. Arfan Ikram,Najaf Amin,Anthony J. Balmforth,Peter S. Braund,Alex S. F. Doney,Angela Döring,Paul Elliott,Tõnu Esko,Oscar H. Franco,Solveig Gretarsdottir,Anna-Liisa Hartikainen,Kauko Heikkilä,Karl-Heinz Herzig,Hilma Holm,Jouke-Jan Hottenga,Elina Hyppönen,Thomas Illig,Aaron Isaacs,Bo Isomaa,Lennart C. Karssen,Johannes Kettunen,Johannes Kettunen,Wolfgang Koenig,Kari Kuulasmaa,Tiina Laatikainen,Jaana Laitinen,Cecilia M. Lindgren,Valeriya Lyssenko,Valeriya Lyssenko,Esa Läärä,Nigel W. Rayner,Nigel W. Rayner,Nigel W. Rayner,Satu Männistö,Anneli Pouta,Anneli Pouta,Wolfgang Rathmann,Fernando Rivadeneira,Aimo Ruokonen,Markku J. Savolainen,Eric J.G. Sijbrands,Kerrin S. Small,Jan Smit,Valgerdur Steinthorsdottir,Ann-Christine Syvänen,Anja Taanila,Martin D. Tobin,André G. Uitterlinden,Sara M. Willems,Gonneke Willemsen,Jacqueline C.M. Witteman,Markus Perola,Markus Perola,Alun Evans,Jean Ferrières,Jarmo Virtamo,Frank Kee,David-Alexandre Trégouët,Dominique Arveiler,Philippe Amouyel,Marco M Ferrario,Paolo Brambilla,Alistair S. Hall,Andrew C. Heath,Pamela A. F. Madden,Nicholas G. Martin,Grant W. Montgomery,John Whitfield,Antti Jula,Paul Knekt,Ben A. Oostra,Cornelia M. van Duijn,Brenda W.J.H. Penninx,George Davey Smith,Jaakko Kaprio,Jaakko Kaprio,Nilesh J. Samani,Nilesh J. Samani,Christian Gieger,Annette Peters,H.-Erich Wichmann,Dorret I. Boomsma,Eco J. C. de Geus,Tiinamaija Tuomi,Chris Power,Christopher J Hammond,Tim D. Spector,Lars Lind,Marju Orho-Melander,Colin N. A. Palmer,Andrew D. Morris,Leif Groop,Leif Groop,Marjo-Riitta Järvelin,Veikko Salomaa,Erkki Vartiainen,Albert Hofman,Samuli Ripatti,Samuli Ripatti,Samuli Ripatti,Andres Metspalu,Unnur Thorsteinsdottir,Unnur Thorsteinsdottir,Kari Stefansson,Kari Stefansson,Nancy L. Pedersen,Mark I. McCarthy,Mark I. McCarthy,Mark I. McCarthy,Erik Ingelsson,Erik Ingelsson,Erik Ingelsson,Inga Prokopenko,Inga Prokopenko,Inga Prokopenko +150 more
TL;DR: In this study, Prokopenko and colleagues provide novel evidence for causal relationship between adiposity and heart failure and increased liver enzymes using a Mendelian randomization study design.
Journal ArticleDOI
Association between genetic variants on chromosome 15q25 locus and objective measures of tobacco exposure.
Marcus R. Munafò,Maria Timofeeva,Richard W Morris,David Prieto-Merino,Naveed Sattar,Paul Brennan,Elaine C. Johnstone,Caroline L Relton,Paul C. D. Johnson,Donna Walther,Peter H. Whincup,Juan P. Casas,George R. Uhl,Paolo Vineis,Sandosh Padmanabhan,Barbara J. Jefferis,Antoinette Amuzu,Elio Riboli,Mark N. Upton,Paul Aveyard,Shah Ebrahim,Aroon D. Hingorani,Graham Watt,Tom Palmer,Nicholas J. Timpson,George Davey Smith +25 more
TL;DR: The data show a stronger association of rs1051730–rs16969968 genotype with objective measures of tobacco exposure compared with self-reported cigarette consumption, which is likely to be mediated largely, if not wholly, via tobacco exposure.
Journal ArticleDOI
Socioeconomic position in childhood and adulthood and insulin resistance: cross sectional survey using data from British women's heart and health study
TL;DR: Adverse social circumstances in childhood, as well as adulthood, are strongly and independently associated with increased risk of insulin resistance and other metabolic risk factors.