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George Davey Smith

Researcher at University of Bristol

Publications -  2646
Citations -  294406

George Davey Smith is an academic researcher from University of Bristol. The author has contributed to research in topics: Population & Mendelian randomization. The author has an hindex of 224, co-authored 2540 publications receiving 248373 citations. Previous affiliations of George Davey Smith include Keele University & Western Infirmary.

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How much of the data published in observational studies of the association between diet and prostate or bladder cancer is usable for meta-analysis?

TL;DR: How often the log odds, risk, or hazard ratio per unit increase in exposure, and its standard error, can be estimated from results reported from observational studies of diet and prostate or bladder cancer so that results are usable in meta-analyses estimating dose-response associations is examined.
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Software Application Profile: PHESANT: a tool for performing automated phenome scans in UK Biobank.

TL;DR: PHESANT (PHEnome Scan ANalysis Tool), a software package for performing comprehensive phenome scans in UK Biobank, uses a novel rule-based algorithm to determine how to appropriately test each trait, then performs the analyses and produces plots and summary tables.
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Social Determinants and the Decline of Cardiovascular Diseases: Understanding the Links

TL;DR: It is argued that understanding patterns and trends of social inequalities in cardiovascular disease and its risk factors requires consideration of the specific intersections of health and social exposures acting across the life course in different settings, in both time and place.
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An atlas of polygenic risk score associations to highlight putative causal relationships across the human phenome

TL;DR: Findings were inverse associations with measures of cognitive function which extensive follow-up analyses using Mendelian randomization provided evidence of a causal relationship and the effect of multiple risk factors on disease using mediation and multivariable MR frameworks.