G
George E Fragoulis
Researcher at National and Kapodistrian University of Athens
Publications - 115
Citations - 1845
George E Fragoulis is an academic researcher from National and Kapodistrian University of Athens. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 16, co-authored 81 publications receiving 1002 citations. Previous affiliations of George E Fragoulis include University of Glasgow.
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JAK-inhibitors. New players in the field of immune-mediated diseases, beyond rheumatoid arthritis
TL;DR: Clinical data, including efficacy and safety, available for JAK inhibitors used in some immune-mediated conditions other than RA are summarized.
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Therapeutic Targeting of IL-17 and IL-23 Cytokines in Immune-Mediated Diseases
TL;DR: Therapeutic agents targeting interleukin-23/-17 and anti-IL-12/-23 regimens appear particularly effective in psoriasis, with promising results in spondyloarthropathies also emerging.
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MicroRNAs in rheumatoid arthritis: From pathogenesis to clinical impact.
Gerasimos Evangelatos,George E Fragoulis,George E Fragoulis,Vassiliki Koulouri,George I. Lambrou +4 more
TL;DR: The research on the miRNA alterations in RA sheds light to several aspects of RA pathogenesis, introduces new biomarkers for RA diagnosis and treatment response prediction and offers the opportunity to discover new, targeted drugs for patients with RA.
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B-cell activating factor genetic variants in lymphomagenesis associated with primary Sjogren's syndrome.
Adrianos Nezos,Aristea Papageorgiou,George E Fragoulis,Dimitrios Ioakeimidis,Michael Koutsilieris,Athanasios G. Tzioufas,Haralampos M. Moutsopoulos,Michael Voulgarelis,Clio P. Mavragani +8 more
TL;DR: The interaction of pSS-related BAFF gene haplotypes together with distinct BAFF genetic variants appears to contribute to this complication, suggesting the implication of the host's genetic background in p SS-related lymphomagenesis.
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Inflammatory bowel diseases and spondyloarthropathies: From pathogenesis to treatment.
George E Fragoulis,Christina Liava,Dimitrios Daoussis,Euangelos Akriviadis,Alexandros Garyfallos,Theodoros Dimitroulas +5 more
TL;DR: Of note, SpA (axial or peripheral) is more commonly observed in Crohn’s disease than in ulcerative colitis, and occurrence of IBD has been associated with AS disease activity.