G
George M. Martin
Researcher at University of Washington
Publications - 385
Citations - 29412
George M. Martin is an academic researcher from University of Washington. The author has contributed to research in topics: Werner syndrome & Gene. The author has an hindex of 77, co-authored 380 publications receiving 28102 citations. Previous affiliations of George M. Martin include Osaka University & Fred Hutchinson Cancer Research Center.
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Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
José Luis Riechmann,Jacqueline E. Heard,George M. Martin,T. Lynne Reuber,Cai-Zhong Jiang,James S. Keddie,Luc Adam,Omaira Pineda,Oliver J. Ratcliffe,Raymond Samaha,Robert A. Creelman,Marsha Pilgrim,Pierre Broun,James Zhang,D. Ghandehari,Bradley K. Sherman,Guo-Liang Yu +16 more
TL;DR: The completion of the Arabidopsis thaliana genome sequence allows a comparative analysis of transcriptional regulators across the three eukaryotic kingdoms and reveals the evolutionary generation of diversity in the regulation of transcription.
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Positional Cloning of the Werner's Syndrome Gene
Chang En Yu,Junko Oshima,Ying-Hui Fu,Ellen M. Wijsman,Fuki M. Hisama,Reid S. Alisch,Shellie Matthews,Jun Nakura,Tetsuro Miki,Samir Ouais,George M. Martin,John Mulligan,Gerard D. Schellenberg +12 more
TL;DR: The identification of a mutated putative helicase as the gene product of the WS gene suggests that defective DNA metabolism is involved in the complex process of aging in WS patients.
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Extension of murine life span by overexpression of catalase targeted to mitochondria.
Samuel E. Schriner,Nancy J. Linford,George M. Martin,Piper M. Treuting,Charles E. Ogburn,Mary J. Emond,Pinar Coskun,Warren Ladiges,Norman S. Wolf,Holly Van Remmen,Douglas C. Wallace,Peter S. Rabinovitch +11 more
TL;DR: Transgenic mice that overexpress human catalase localized to the peroxisome, the nucleus, or mitochondria were generated and the importance of mitochondria as a source of radicals was reinforced.
Journal Article
Replicative life-span of cultivated human cells. Effects of donor's age, tissue, and genotype.
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Genetic linkage evidence for a familial Alzheimer's disease locus on chromosome 14.
Gerard D. Schellenberg,Thomas D. Bird,Ellen M. Wijsman,Harry T. Orr,Leojean Anderson,Ellen Nemens,June A. White,Lori L.C. Bonnycastle,James L. Weber,M. Elisa Alonso,Huntington Potter,Leonard L. Heston,George M. Martin +12 more
TL;DR: Evidence indicates a familial Alzheimer's disease locus on chromosome 14, which is found in early-onset non-Volga German kindreds, and results for the Volga German families were either negative or nonsignificant for markers in this region.