G
George M. Whitesides
Researcher at Harvard University
Publications - 1754
Citations - 287794
George M. Whitesides is an academic researcher from Harvard University. The author has contributed to research in topics: Monolayer & Self-assembled monolayer. The author has an hindex of 240, co-authored 1739 publications receiving 269833 citations. Previous affiliations of George M. Whitesides include University of California, Davis & University of Texas at Austin.
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Activation parameters for thiolate-disulfide interchange reactions in aqueous solution
TL;DR: In this paper, the activation parameters for thiolate-disulfide interchange reactions in water were measured and two disulfides were examined (Ellman's reagent and oxidized glutathione) and three thiols (2-mercaptoethanol, 1,3dithio-propan-2-ol, and 1,4-dithiothreitol).
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Palladium as a substrate for self-assembled monolayers used in biotechnology.
TL;DR: Self-assembled monolayers on palladium that resist the nonspecific adsorption of proteins and the adhesion of mammalian cells are described.
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Thermodynamic parameters for the association of fluorinated benzenesulfonamides with bovine carbonic anhydrase II.
Vijay M. Krishnamurthy,Brooks R. Bohall,Chu-Young Kim,Demetri T. Moustakas,David W. Christianson,George M. Whitesides +5 more
TL;DR: Calorimetry revealed that all of the ligands studied bind in a 1:1 stoichiometry with BCA; this result was confirmed by 19F NMR spectroscopy and X-ray crystallography (for complexes with human carbonic anhydrase II).
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The Binding of Benzoarylsulfonamide Ligands to Human Carbonic Anhydrase is Insensitive to Formal Fluorination of the Ligand
Matthew R. Lockett,Heiko Lange,Benjamin Breiten,Annie Heroux,Woody Sherman,Dmitrij Rappoport,Patricia O. Yau,Philip W. Snyder,George M. Whitesides,George M. Whitesides +9 more
TL;DR: Pairs of benzo- and perfluorobenzoarylsulfonamide ligands bind to human carbonic anhydrase with a conserved binding geometry, an enthalpy-driven binding, and indistinguishable binding affinities, which support the pervasive theory that the lock-and-key model disregards an important component of binding.
Journal ArticleDOI
ac electric fields drive steady flows in flames.
Aaron M. Drews,Ludovico Cademartiri,Michael Chemama,Michael Brenner,George M. Whitesides,Kyle J. M. Bishop +5 more
TL;DR: It is shown that time-oscillating electric fields applied to plasmas present in flames create steady flows of gas and how δ decreases as the frequency of the applied field increases is revealed.