G
George M. Yousef
Researcher at University of Toronto
Publications - 210
Citations - 10586
George M. Yousef is an academic researcher from University of Toronto. The author has contributed to research in topics: Cancer & Kallikrein. The author has an hindex of 59, co-authored 207 publications receiving 9609 citations. Previous affiliations of George M. Yousef include York University & St. Michael's GAA, Sligo.
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Journal ArticleDOI
Liquid biopsy: a step forward towards precision medicine in urologic malignancies
Ashley Di Meo,Ashley Di Meo,Jenni Bartlett,Jenni Bartlett,Yufeng Cheng,Maria D. Pasic,George M. Yousef,George M. Yousef +7 more
TL;DR: An overview of the current state of cell-free DNA-based kidney, prostate and bladder cancer biomarker research is provided and the potential utility other circulating molecules are discussed.
Journal Article
Endoglin (CD105): a review of its role in angiogenesis and tumor diagnosis, progression and therapy.
Farshad Nassiri,Michael D. Cusimano,Bernd W. Scheithauer,Fabio Rotondo,Alessandra Fazio,George M. Yousef,Luis V. Syro,Kalman Kovacs,Ricardo V. Lloyd +8 more
TL;DR: This review details the structure and function of endoglin, and investigates the role ofendoglin in angiogenesis and tumor diagnosis, prognosis, and therapy.
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Differential expression profiling of microRNAs and their potential involvement in renal cell carcinoma pathogenesis.
Tsz-fung F. Chow,Youssef M. Youssef,Evi Lianidou,Alexander D. Romaschin,Alexander D. Romaschin,R. John D'a. Honey,Robert Stewart,Kenneth T. Pace,George M. Yousef,George M. Yousef +9 more
TL;DR: A miRNA microarray analysis identified miRNAs that are dysregulated in ccRCC and bioinformatics analysis suggests that these mi RNAs may be involved in cancer pathogenesis and have the potential to be biomarkers.
Journal ArticleDOI
Accurate Molecular Classification of Kidney Cancer Subtypes Using MicroRNA Signature
Youssef M. Youssef,Nicole M.A. White,Nicole M.A. White,Jörg Grigull,Adriana Krizova,Adriana Krizova,Christina Samy,Christina Samy,Salvador Mejia-Guerrero,Salvador Mejia-Guerrero,Andrew Evans,Andrew Evans,George M. Yousef,George M. Yousef +13 more
TL;DR: A classification system that can distinguish the different RCC subtypes using unique miRNA signatures in a maximum of four steps is developed and the oncogenesis of ccRCC is more closely related to pRCC, whereas chR CC is comparable with oncocytoma.
Journal ArticleDOI
Human Kallikrein 6 (hK6): A New Potential Serum Biomarker for Diagnosis and Prognosis of Ovarian Carcinoma
Eleftherios P. Diamandis,Andreas Scorilas,S. Fracchioli,Marleen Van Gramberen,Henk W.A. de Bruijn,Alfthan Henrik,Antoninus Soosaipillai,Linda Grass,George M. Yousef,Ulf-Håkan Stenman,Marco Massobrio,Ate G.J. van der Zee,Ignace Vergote,Dionyssios Katsaros +13 more
TL;DR: Serum hK6 concentration seems to be a new biomarker for ovarian carcinoma and may have value for disease diagnosis and prognosis and is a powerful predictor of disease-free and overall survival in both univariate and multivariate analyses.