G
George Thomas
Researcher at Rajiv Gandhi Centre for Biotechnology
Publications - 30
Citations - 469
George Thomas is an academic researcher from Rajiv Gandhi Centre for Biotechnology. The author has contributed to research in topics: Zingiber zerumbet & Genetic diversity. The author has an hindex of 12, co-authored 27 publications receiving 415 citations.
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Journal ArticleDOI
Calpain and reactive oxygen species targets Bax for mitochondrial permeabilisation and caspase activation in zerumbone induced apoptosis.
Praveen K. Sobhan,Mahendra Seervi,Lokesh Deb,Saneesh Varghese,Anjana Soman,Jeena Joseph,Krupa Ann Mathew,Godi Raghu,George Thomas,E. Sreekumar,Manjula S,Santosh Kumar T. R +11 more
TL;DR: These studies substantiate that mitochondrial permeabilisation and cytochrome c dependent caspase activation dominate in zerumbone induced cell death and confirm the essential role of Bax for mitochondrial permeabilsation.
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Engineering sugarcane cultivars with bovine pancreatic trypsin inhibitor (aprotinin) gene for protection against top borer (Scirpophaga excerptalis Walker).
Leela Amala Christy,S. Arvinth,M. Saravanakumar,M. Kanchana,N. Mukunthan,J. Srikanth,George Thomas,N. Subramonian +7 more
TL;DR: Results of this study show the possibility of deploying aprotinin gene for the development of transgenic sugarcane cultivars resistant to top borer and larvae of top borers fed on transgenics showed significant reduction in larval weight which indicated impairment of their development.
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Isolation, characterization and expression studies of resistance gene candidates (RGCs) from Zingiber spp.
R. Aswati Nair,George Thomas +1 more
TL;DR: The isolation and characterization of RGCs from ginger and its wild relatives are reported for the first time, which will serve as a potential resource for future improvement of this important vegetatively propagated spice crop.
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Population genetic structure of the clonal plant Zingiber zerumbet (L.) Smith (Zingiberaceae), a wild relative of cultivated ginger, and its response to Pythium aphanidermatum
P. G. Kavitha,George Thomas +1 more
TL;DR: The study revealed high genetic diversity and variability for pathogen resistance among Z. zerumbet accessions and confirmed the value of Z.Zingiber zerUMet as a potential donor for soft rot resistance for the genetic improvement of ginger.
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Molecular Characterization of an Oomycete-Responsive PR-5 Protein Gene from Zingiber zerumbet
TL;DR: A member of the pathogenesis-related protein group 5 (PR-5) gene family is identified in Z. zerumbet that is expressed constitutively but upregulated in response to infection by P. aphanidermatum and elucidation of the molecular mechanism of ZzPR5 may provide important insight toward engineering soft rot resistance into the obligatory asexual ginger.