G
Gerald Z. Hertz
Researcher at University of Colorado Boulder
Publications - 12
Citations - 2944
Gerald Z. Hertz is an academic researcher from University of Colorado Boulder. The author has contributed to research in topics: Consensus sequence & Recombination. The author has an hindex of 9, co-authored 12 publications receiving 2883 citations.
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Journal ArticleDOI
Identifying DNA and protein patterns with statistically significant alignments of multiple sequences.
Gerald Z. Hertz,Gary D. Stormo +1 more
TL;DR: A greedy algorithm for determining alignments of functionally related sequences is described, and the accuracy of the P value calculations are tested, and an example of using the algorithm to identify binding sites for the Escherichia coli CRP protein is given.
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Splicing signals in Drosophila: intron size, information content, and consensus sequences
TL;DR: A database of 209 Drosophila introns was extracted from Genbank and examined by a number of methods in order to characterize features that might serve as signals for messenger RNA splicing and found that there is a discontinuity in A + T content between exons and introns, which are A +T rich.
Journal ArticleDOI
Identification of consensus patterns in unaligned DNA sequences known to be functionally related.
TL;DR: A method for identifying consensus patterns in a set of unaligned DNA sequences known to bind a common protein or to have some other common biochemical function is developed, based on a matrix representation of binding site patterns.
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Identifying constraints on the higher-order structure of RNA: continued development and application of comparative sequence analysis methods
TL;DR: Developing more rigorous comparative analysis protocols on tRNA, 16S and 23S rRNA are substantiating previously proposed associations and are now beginning to reveal additional constraints on these molecules.
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DNA sequences at immunoglobulin switch region recombination sites
TL;DR: A model for switch recombination that involves illegitimate priming of one switch region on another, followed by error-prone DNA synthesis, is proposed and does not appear to occur by homologous recombination.