Gerd Becker

TL;DR: Radiotherapy directed toward the craniospinal axis or tumor site alone at decreased dose levels is effective and further attempts to decrease total doses are justified to reduce the risk of late side effects.

TL;DR: All system components are aimed at conforming dose distributions for fractionated radiotherapy treatments to the target to improve sparing of adjacent normal tissues, and at achieving a sufficient geometrical accuracy in the dose application.

TL;DR: Conventional radiation therapy of pituitary adenoma is highly effective and should be recommended after subtotal resection of primary tumors such as macroadenomas, after gross total resection from endocrine active adenomas with postsurgical hormone secretion and for recurrent tumors.

TL;DR: St stereotactic fractionated conformal irradiation is an effective treatment option for primary ONSM with minimal treatment related morbidity and should be considered as therapeutic option both in early stage ONSM where surgery cannot be justified as well as in later stages, where surgery is so far considered the first line approach.

TL;DR: SFRT represents a very effective and low-toxic treatment modality for ONSM and adds substantial evidence that SFRT may definitely become a standard treatment approach in selected cases of ONSM.