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Gert Jacobus Laubscher
Researcher at Stellenbosch University
Publications - 17
Citations - 821
Gert Jacobus Laubscher is an academic researcher from Stellenbosch University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 5, co-authored 10 publications receiving 107 citations.
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Persistent clotting protein pathology in Long COVID/ Post-Acute Sequelae of COVID-19 (PASC) is accompanied by increased levels of antiplasmin
Etheresia Pretorius,Maré Vlok,Chantelle Venter,Johannes A. Bezuidenhout,Gert Jacobus Laubscher,Janami Steenkamp,Douglas B. Kell,Douglas B. Kell,Douglas B. Kell +8 more
TL;DR: Clotting pathologies in both acute COVID-19 infection and in Long COVID/PASC might therefore benefit from following a regime of continued anticlotting therapy to support the fibrinolytic system function.
Journal ArticleDOI
Persistent clotting protein pathology in Long COVID/Post-Acute Sequelae of COVID-19 (PASC) is accompanied by increased levels of antiplasmin.
Etheresia Pretorius,Maré Vlok,Chantelle Venter,Johannes A. Bezuidenhout,Gert Jacobus Laubscher,Janami Steenkamp,Douglas B. Kell,Douglas B. Kell,Douglas B. Kell +8 more
TL;DR: In this article, the authors used proteomics and fluorescence microscopy to study plasma samples from healthy individuals, individuals with Type 2 Diabetes Mellitus (T2DM), with acute COVID-19, and those with Long COVID/PASC symptoms.
Journal ArticleDOI
Covid-19: The Rollercoaster of Fibrin(Ogen), D-Dimer, Von Willebrand Factor, P-Selectin and Their Interactions with Endothelial Cells, Platelets and Erythrocytes.
Corlia Grobler,Siphosethu C. Maphumulo,L. Mireille Grobbelaar,Jhade C. Bredenkamp,Gert Jacobus Laubscher,Petrus Johannes Lourens,Janami Steenkamp,Douglas B. Kell,Douglas B. Kell,Douglas B. Kell,Etheresia Pretorius +10 more
TL;DR: Vascular implications of COVID-19 and relate this to circulating biomarker, endothelial, erythrocyte and platelet dysfunction are discussed and it is suggested that a personalized medicine approach should be considered in the treatment of patients.
Journal ArticleDOI
SARS-CoV-2 spike protein S1 induces fibrin(ogen) resistant to fibrinolysis: implications for microclot formation in COVID-19.
Lize M Grobbelaar,Chantelle Venter,Maré Vlok,Malebogo Ngoepe,Malebogo Ngoepe,Gert Jacobus Laubscher,Petrus Johannes Lourens,Janami Steenkamp,Douglas B. Kell,Douglas B. Kell,Douglas B. Kell,Etheresia Pretorius +11 more
TL;DR: In this paper, the effect of isolated SARS-CoV-2 spike protein S1 subunit as potential inflammagen sui generis was investigated using scanning electron and fluorescence microscopy as well as mass spectrometry, and the potential of this inflammagen to interact with platelets and fibrin(ogen) directly to cause blood hypercoagulation.
Journal ArticleDOI
Prevalence of symptoms, comorbidities, fibrin amyloid microclots and platelet pathology in individuals with Long COVID/Post-Acute Sequelae of COVID-19 (PASC)
Etheresia Pretorius,Chantelle Venter,Gert Jacobus Laubscher,Maritha J. Kotze,S. O. Oladejo,Liam Watson,Kanshu Rajaratnam,B Watson,Douglas B. Kell +8 more
TL;DR: In this article , the authors report on the comorbidities and persistent symptoms, using data obtained from 845 South African Long COVID-19 (PASC) patients, and suggest that their platelet and clotting grading system provides a simple and cost-effective diagnostic method for early detection of long COVID/PASC as a major determinant of effective treatment.