G
Ghislain Rocheleau
Researcher at McGill University
Publications - 27
Citations - 9255
Ghislain Rocheleau is an academic researcher from McGill University. The author has contributed to research in topics: Population & Medicine. The author has an hindex of 12, co-authored 18 publications receiving 8635 citations. Previous affiliations of Ghislain Rocheleau include Icahn School of Medicine at Mount Sinai & Centre national de la recherche scientifique.
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Journal ArticleDOI
A genome-wide association study identifies novel risk loci for type 2 diabetes
Robert Sladek,Ghislain Rocheleau,Johan Rung,Christian Dina,Lishuang Shen,David Serre,Philippe Boutin,Daniel Vincent,Alexandre Belisle,Samy Hadjadj,Beverley Balkau,Barbara Heude,Guillaume Charpentier,Thomas J. Hudson,Thomas J. Hudson,Alexandre Montpetit,Alexey V. Pshezhetsky,Marc Prentki,Barry I. Posner,David J. Balding,David Meyre,Constantin Polychronakos,Philippe Froguel,Philippe Froguel +23 more
TL;DR: Four loci containing variants that confer type 2 diabetes risk are identified and constitute proof of principle for the genome-wide approach to the elucidation of complex genetic traits.
Journal ArticleDOI
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
Josée Dupuis,Josée Dupuis,Claudia Langenberg,Inga Prokopenko,Richa Saxena,Richa Saxena,Nicole Soranzo,Nicole Soranzo,Anne U. Jackson,Eleanor Wheeler,Nicole L. Glazer,Nabila Bouatia-Naji,Anna L. Gloyn,Cecilia M. Lindgren,Reedik Mägi,Andrew P. Morris,Joshua C. Randall,Toby Johnson,Toby Johnson,Paul Elliott,Paul Elliott,Denis Rybin,Gudmar Thorleifsson,Valgerdur Steinthorsdottir,Peter Henneman,Harald Grallert,Abbas Dehghan,Jouke JanHottenga,Christopher S. Franklin,Pau Navarro,Kijoung Song,Anuj Goel,John R. B. Perry,Josephine M. Egan,Taina K. Lajunen,Niels Grarup,Thomas Sparsø,Alex S. F. Doney,Benjamin F. Voight,Benjamin F. Voight,Heather M. Stringham,Man Li,Stavroula Kanoni,Peter Shrader,Christine Cavalcanti-Proença,Meena Kumari,Lu Qi,Nicholas J. Timpson,Christian Gieger,Carina Zabena,Ghislain Rocheleau,Erik Ingelsson,Erik Ingelsson,Ping An,Jeffrey R. O'Connell,Jian'an Luan,Amanda F. Elliott,Amanda F. Elliott,Steven A. McCarroll,Steven A. McCarroll,Felicity Payne,Rosa Maria Roccasecca,François Pattou,Praveen Sethupathy,Kristin Ardlie,Yavuz Ariyurek,Beverley Balkau,Philip J. Barter,John Beilby,Yoav Ben-Shlomo,Rafn Benediktsson,Amanda J. Bennett,Sven Bergmann,Sven Bergmann,Murielle Bochud,Eric Boerwinkle,Amélie Bonnefond,Lori L. Bonnycastle,Knut Borch-Johnsen,Knut Borch-Johnsen,Yvonne Böttcher,Eric J. Brunner,Suzannah Bumpstead,Guillaume Charpentier,Yii Der IdaChen,Peter S. Chines,Robert Clarke,Lachlan J. McOin,Mark E. Cooper,Marilyn C. Cornelis,Gabe Crawford,Laura Crisponi,Ian N. M. Day,Eco J. C. de Geus,Jérôme Delplanque,Christian Dina,Michael R. Erdos,A C Fedson,Antje Fischer-Rosinsky,Nita G. Forouhi,Caroline S. Fox,Caroline S. Fox,Rune R. Frants,Maria GraziaFranzosi,Pilar Galan,Mark O. Goodarzi,J. Graessler,Christopher J. Groves,Scott M. Grundy,Rhian Gwilliam,Ulf Gyllensten,Samy Hadjadj,Göran Hallmans,Naomi Hammond,Xijing Han,Anna LiisaHartikainen,Neelam Hassanali,Caroline Hayward,Simon Heath,Serge Hercberg,Christian Herder,Andrew A. Hicks,David R. Hillman,Aroon D. Hingorani,Albert Hofman,Jennie Hui,Joseph Hung,Joseph Hung,Bo Isomaa,Paul Johnson,Torben Jørgensen,Antti Jula,Marika Kaakinen,Jaakko Kaprio,Jaakko Kaprio,Y. AnteroKesaniemi,Mika Kivimäki,Beatrice Knight,Seppo Koskinen,Peter Kovacs,Kirsten Ohm Kyvik,G. Mark Lathrop,Debbie A Lawlor,Olivier Le Bacquer,Cécile Lecoeur,Yun Li,Valeriya Lyssenko,Robert W. Mahley,Massimo Mangino,Alisa K. Manning,María TeresaMartínez-Larrad,Jarred B. McAteer,Jarred B. McAteer,Laura J. McCulloch,Ruth McPherson,Christa Meisinger,David Melzer,David Meyre,Braxton D. Mitchell,Mario A. Morken,Sutapa Mukherjee,Silvia Naitza,Narisu Narisu,Matt Neville,Ben A. Oostra,Marco Orrù,Ruth E. Pakyz,Colin N. Apalmer,Giuseppe Paolisso,Cristian Pattaro,Daniel S. Pearson,John F. Peden,Nancy L. Pedersen,Markus Perola,Markus Perola,Andreas Pfeiffer,Irene Pichler,Ozren Polasek,Danielle Posthuma,Simon C. Potter,Anneli Pouta,Michael A. Province,Bruce M. Psaty,Bruce M. Psaty,Wolfgang Rathmann,Nigel W. Rayner,Kenneth Rice,Samuli Ripatti,Samuli Ripatti,Fernando Rivadeneira,Michael Roden,Olov Rolandsson,Annelli Sandbæk,Manjinder S. Sandhu,Serena Sanna,Avan Aihie Sayer,Paul Scheet,Laura J. Scott,Udo Seedorf,Stephen J. Sharp,Beverley M. Shields,Gunnar Sigursson,Eric J.G. Sijbrands,Angela Silveira,Laila Simpson,Andrew B. Singleton,Nicholas L. Smith,Nicholas L. Smith,Ulla Sovio,Amy J. Swift,Holly E. Syddall,Ann ChristineSyvänen,Toshiko Tanaka,Toshiko Tanaka,Barbara Thorand,Jean Tichet,Anke Tönjes,Tiinamaija Tuomi,André G. Uitterlinden,Ko Willems van Dijk,Mandy van Hoek,Dhiraj Varma,Sophie Visvikis-Siest,Veronique Vitart,Nicole Vogelzangs,Gerard Waeber,Peter Wagner,Peter Wagner,Andrew Walley,G. BragiWalters,Kim L. Ward,Hugh Watkins,Michael N. Weedon,Sarah H. Wild,Gonneke Willemsen,Jaqueline C. MWitteman,John W. GYarnell,Eleftheria Zeggini,Eleftheria Zeggini,Diana Zelenika,Björn Zethelius,Björn Zethelius,Guangju Zhai,Jing Hua Zhao,M. Carola Zillikens,Ingrid B. Borecki,Ruth J. F. Loos,Pierre Meneton,Patrik K. E. Magnusson,David M. Nathan,Gordon H. Williams,Andrew T. Hattersley,Kaisa Silander,Kaisa Silander,Veikko Salomaa,George Davey Smith,Stefan R. Bornstein,Peter Schwarz,Joachim Spranger,Fredrik Karpe,Alan R. Shuldiner,Cyrus Cooper,George Dedoussis,Manuel Serrano-Ríos,Andrew D. Morris,Lars Lind,Lyle J. Palmer,Lyle J. Palmer,Frank B. Hu,Paul W. Franks,Shah Ebrahim,Michael Marmot,W. H. Linda Kao,James S. Pankow,Mike Sampson,Johanna Kuusisto,Markku Laakso,Torben Hansen,Torben Hansen,Oluf Pedersen,Oluf Pedersen,Oluf Pedersen,Peter P. Pramstaller,H.-Erich Wichmann,Thomas Illig,Igor Rudan,Igor Rudan,Alan F. Wright,Michael Stumvoll,Harry Campbell,James F. Wilson,Richard N. Bergman,Thomas A. Buchanan,Francis S. Collins,Karen L. Mohlke,Jaakko Tuomilehto,Jaakko Tuomilehto,Timo T. Valle,David Altshuler,David Altshuler,Jerome I. Rotter,David S. Siscovick,Brenda W.J.H. Penninx,Dorret I. Boomsma,Panos Deloukas,Tim D. Spector,Tim D. Spector,Timothy M. Frayling,Luigi Ferrucci,Augustine Kong,Unnur Thorsteinsdottir,Unnur Thorsteinsdottir,Kari Stefansson,Kari Stefansson,Cornelia M. van Duijn,Yurii S. Aulchenko,Antonio Cao,Angelo Scuteri,David Schlessinger,Manuela Uda,Aimo Ruokonen,Marjo Riitta-Järvelin,Marjo Riitta-Järvelin,Dawn M. Waterworth,Peter Vollenweider,Leena Peltonen,Vincent Mooser,Gonçalo R. Abecasis,Nicholas J. Wareham,Robert Sladek,Philippe Froguel,Philippe Froguel,Richard M. Watanabe,James B. Meigs,Leif Groop,Michael Boehnke,Mark I. McCarthy,Jose C. Florez,Jose C. Florez,Inês Barroso +339 more
TL;DR: It is demonstrated that genetic studies of glycemic traits can identify type 2 diabetes risk loci, as well as loci containing gene variants that are associated with a modest elevation in glucose levels but are not associated with overt diabetes.
Journal ArticleDOI
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis
Benjamin F. Voight,Benjamin F. Voight,Laura J. Scott,Valgerdur Steinthorsdottir,Andrew P. Morris,Christian Dina,Christian Dina,Ryan P. Welch,Eleftheria Zeggini,Eleftheria Zeggini,Cornelia Huth,Yurii S. Aulchenko,Gudmar Thorleifsson,Laura J. McCulloch,Teresa Ferreira,Harald Grallert,Najaf Amin,Guanming Wu,Cristen J. Willer,Soumya Raychaudhuri,Soumya Raychaudhuri,Soumya Raychaudhuri,Steve McCarroll,Steve McCarroll,Claudia Langenberg,Oliver Hofmann,Josée Dupuis,Lu Qi,Lu Qi,Ayellet V. Segrè,Ayellet V. Segrè,Mandy van Hoek,Pau Navarro,Kristin Ardlie,Beverley Balkau,Rafn Benediktsson,Amanda J. Bennett,Roza Blagieva,Eric Boerwinkle,Lori L. Bonnycastle,Kristina Bengtsson Boström,Bert Bravenboer,Suzannah Bumpstead,N P Burtt,Guillaume Charpentier,Peter S. Chines,Marilyn C. Cornelis,David Couper,Gabe Crawford,Alex S. F. Doney,Katherine S. Elliott,Amanda F. Elliott,Amanda F. Elliott,Michael R. Erdos,Caroline S. Fox,Christopher S. Franklin,Martha Ganser,Christian Gieger,Niels Grarup,Todd Green,Todd Green,Simon J. Griffin,Christopher J. Groves,Candace Guiducci,Samy Hadjadj,Neelam Hassanali,Christian Herder,Bo Isomaa,Anne U. Jackson,Paul Johnson,Torben Jørgensen,Torben Jørgensen,Wen H. L. Kao,Norman Klopp,Augustine Kong,Peter Kraft,Johanna Kuusisto,Torsten Lauritzen,Man Li,Aloysius G Lieverse,Cecilia M. Lindgren,Valeriya Lyssenko,Michel Marre,Michel Marre,Thomas Meitinger,Kristian Midthjell,Mario A. Morken,Narisu Narisu,Peter M. Nilsson,Katharine R. Owen,Felicity Payne,John R. B. Perry,Ann-Kristin Petersen,Carl G. P. Platou,Christine Proença,Inga Prokopenko,Inga Prokopenko,Wolfgang Rathmann,N. William Rayner,N. William Rayner,Neil R. Robertson,Neil R. Robertson,Ghislain Rocheleau,Michael Roden,Mike Sampson,Richa Saxena,Richa Saxena,Beverley M. Shields,Peter Shrader,Gunnar Sigurdsson,Thomas Sparsø,Klaus Strassburger,Heather M. Stringham,Qi Sun,Amy J. Swift,Barbara Thorand,Jean Tichet,Tiinamaija Tuomi,Rob M. van Dam,Timon W. van Haeften,Thijs T. W. van Herpt,Jana V. van Vliet-Ostaptchouk,G. Bragi Walters,Michael N. Weedon,Cisca Wijmenga,Jacqueline C. M. Witteman,Richard N. Bergman,Stéphane Cauchi,Francis S. Collins,Anna L. Gloyn,Ulf Gyllensten,Torben Hansen,Winston Hide,Graham A. Hitman,Albert Hofman,David J. Hunter,Kristian Hveem,Markku Laakso,Karen L. Mohlke,Andrew D. Morris,Colin N. A. Palmer,Peter P. Pramstaller,Igor Rudan,Igor Rudan,Eric J.G. Sijbrands,Lincoln Stein,Jaakko Tuomilehto,Jaakko Tuomilehto,André G. Uitterlinden,Mark Walker,Nicholas J. Wareham,Richard M. Watanabe,Gonçalo R. Abecasis,Bernhard O. Boehm,Harry Campbell,Mark J. Daly,Mark J. Daly,Andrew T. Hattersley,Frank B. Hu,Frank B. Hu,James B. Meigs,James S. Pankow,Oluf Pedersen,H-Erich Wichmann,Inês Barroso,Jose C. Florez,Timothy M. Frayling,Leif Groop,Leif Groop,Robert Sladek,Unnur Thorsteinsdottir,Unnur Thorsteinsdottir,James F. Wilson,Thomas Illig,Philippe Froguel,Philippe Froguel,Cornelia M. van Duijn,Kari Stefansson,Kari Stefansson,David Altshuler,Michael Boehnke,Mark I. McCarthy,Mark I. McCarthy,Mark I. McCarthy +183 more
TL;DR: By combining genome-wide association data from 8,130 individuals with type 2 diabetes and 38,987 controls of European descent and following up previously unidentified meta-analysis signals, 12 new T2D association signals are identified with combined P < 5 × 10−8.
Journal ArticleDOI
A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk
Nabila Bouatia-Naji,Amélie Bonnefond,Amélie Bonnefond,Christine Cavalcanti-Proença,Christine Cavalcanti-Proença,Thomas Sparsø,Johan Holmkvist,Marion Marchand,Marion Marchand,Jérôme Delplanque,Jérôme Delplanque,Stéphane Lobbens,Stéphane Lobbens,Ghislain Rocheleau,Emmanuelle Durand,Emmanuelle Durand,Franck De Graeve,Franck De Graeve,Jean-Claude Chèvre,Jean-Claude Chèvre,Knut Borch-Johnsen,Anna-Liisa Hartikainen,Aimo Ruokonen,Jean Tichet,Michel Marre,Michel Marre,Jacques Weill,Barbara Heude,Barbara Heude,Maithé Tauber,Katleen Lemaire,Frans Schuit,Paul Elliott,Torben Jørgensen,Guillaume Charpentier,Samy Hadjadj,Stéphane Cauchi,Stéphane Cauchi,Martine Vaxillaire,Martine Vaxillaire,Robert Sladek,Sophie Visvikis-Siest,Beverley Balkau,Beverley Balkau,Claire Levy-Marchal,Claire Levy-Marchal,François Pattou,David Meyre,David Meyre,Alexandra I. F. Blakemore,M. R. Järvelin,M. R. Järvelin,Andrew Walley,Torben Hansen,Christian Dina,Christian Dina,Oluf Pedersen,Oluf Pedersen,Philippe Froguel,Philippe Froguel,Philippe Froguel +60 more
TL;DR: The data suggest a possible link between circadian rhythm regulation and glucose homeostasis through the melatonin signaling pathway and show MT2 expression in human pancreatic islets and beta cells.
Journal ArticleDOI
Novel Loci for Adiponectin Levels and Their Influence on Type 2 Diabetes and Metabolic Traits: A Multi-Ethnic Meta-Analysis of 45,891 Individuals
Zari Dastani,Hivert M-F.,Hivert M-F.,N J Timpson,Perry Jrb.,Perry Jrb.,Xin Yuan,Robert A. Scott,Peter Henneman,Iris M. Heid,Jorge R. Kizer,Lyytikäinen L-P.,Christian Fuchsberger,Toshiko Tanaka,Toshiko Tanaka,Andrew P. Morris,Kerrin S. Small,Kerrin S. Small,Aaron Isaacs,Marian Beekman,Stefan Coassin,Kurt Lohman,Lu Qi,Stavroula Kanoni,Stavroula Kanoni,James S. Pankow,Uh H-W.,Ying Wu,Aurelian Bidulescu,Laura J. Rasmussen-Torvik,Greenwood Cmt.,Martin Ladouceur,Jonna L. Grimsby,Alisa K. Manning,Liu C-T.,Jaspal S. Kooner,Vincent Mooser,Peter Vollenweider,Karen Kapur,John C. Chambers,Nicholas J. Wareham,Claudia Langenberg,Rune R. Frants,K Willems-Vandijk,Ben A. Oostra,Sara M. Willems,Claudia Lamina,Thomas W. Winkler,Bruce M. Psaty,Bruce M. Psaty,Russel Tracy,Jennifer A. Brody,I Chen,J. Viikari,Mika Kähönen,Peter P. Pramstaller,David M. Evans,B. St Pourcain,Naveed Sattar,Andrew R. Wood,Stefania Bandinelli,Olga D. Carlson,Josephine M. Egan,Stefan Böhringer,D. van Heemst,Lyudmyla Kedenko,Kati Kristiansson,Nuotio M-L.,Loo B-M.,T.B. Harris,Melissa Garcia,Alka M. Kanaya,Margot Haun,Norman Klopp,Wichmann H-E.,Panos Deloukas,Panos Deloukas,E Katsareli,David Couper,Bruce Bartholow Duncan,Bruce Bartholow Duncan,M. Kloppenburg,Linda S. Adair,Judith B. Borja,James G. Wilson,Solomon K. Musani,Xiuqing Guo,Toby Johnson,Toby Johnson,Toby Johnson,Robert K. Semple,Tanya M. Teslovich,Tanya M. Teslovich,Matthew A. Allison,Susan Redline,Sarah G. Buxbaum,Karen L. Mohlke,Ingrid Meulenbelt,Christie M. Ballantyne,George Dedoussis,Frank B. Hu,Yongmei Liu,Bernhard Paulweber,Tim D. Spector,P E Slagboom,Luigi Ferrucci,Antti Jula,Markus Perola,Olli T. Raitakari,Jose C. Florez,Jose C. Florez,Jose C. Florez,Veikko Salomaa,Johan G. Eriksson,Timothy M. Frayling,Andrew A. Hicks,Terho Lehtimäki,George Davey Smith,David S. Siscovick,Florian Kronenberg,C.M. van Duijn,C.M. van Duijn,Loos Rjf.,Loos Rjf.,Dawn M. Waterworth,James B. Meigs,Josée Dupuis,Josée Dupuis,J B Richards,Benjamin F. Voight,Benjamin F. Voight,Benjamin F. Voight,Laura J. Scott,Valgerdur Steinthorsdottir,Christian Dina,Ryan P. Welch,Eleftheria Zeggini,Eleftheria Zeggini,Cornelia Huth,Yurii S. Aulchenko,Gudmar Thorleifsson,Laura J. McCulloch,Teresa Ferreira,Harald Grallert,Najaf Amin,G Wu,Cristen J. Willer,Soumya Raychaudhuri,Soumya Raychaudhuri,Steven A. McCarroll,Oliver Hofmann,Ayellet V. Segrè,Ayellet V. Segrè,M. van Hoek,M. van Hoek,Pau Navarro,Kristin G. Ardlie,Beverley Balkau,Beverley Balkau,Rafn Benediktsson,Amanda J. Bennett,Roza Blagieva,Eric Boerwinkle,Lori L. Bonnycastle,K B Boström,Bert Bravenboer,S Bumpstead,N P Burtt,Guillaume Charpentier,P S Chines,Marilyn C. Cornelis,G Crawford,G Crawford,Doney Asf.,Katherine S. Elliott,A L Elliott,Michael R. Erdos,Caroline S. Fox,Caroline S. Fox,Christopher S. Franklin,Martha Ganser,Christian Gieger,Niels Grarup,Todd Green,Todd Green,Simon J. Griffin,Christopher J. Groves,Candace Guiducci,Samy Hadjadj,Neelam Hassanali,Christian Herder,Bo Isomaa,Anne U. Jackson,Johnson Prv.,Torben Jørgensen,Kao Whl.,Augustine Kong,Peter Kraft,Johanna Kuusisto,T. Lauritzen,M Li,Aloysius G Lieverse,Cecilia M. Lindgren,Valeriya Lyssenko,Michel Marre,Thomas Meitinger,Kristian Midthjell,Mario A. Morken,Narisu Narisu,Peter M. Nilsson,Katharine R. Owen,Felicity Payne,Petersen A-K.,Carl G. P. Platou,Christine Proença,Inga Prokopenko,Wolfgang Rathmann,Nigel W. Rayner,Neil R. Robertson,Ghislain Rocheleau,Michael Roden,Mike Sampson,Richa Saxena,Richa Saxena,Richa Saxena,B M Shields,Peter Shrader,Gunnar Sigurdsson,Thomas Sparsø,Klaus Strassburger,Heather M. Stringham,Qi Sun,A J Swift,Barbara Thorand,Jean Tichet,Tiinamaija Tuomi,R. M. van Dam,T.W. van Haeften,T van Herpt,J. V. van Vliet-Ostaptchouk,G B Walters,Michael N. Weedon,Cisca Wijmenga,Jacqueline C. M. Witteman,Richard N. Bergman,Stéphane Cauchi,Francis S. Collins,Anna L. Gloyn,Ulf Gyllensten,Torben Hansen,Torben Hansen,Torben Hansen,Winston Hide,Graham A. Hitman,Albert Hofman,David J. Hunter,Kristian Hveem,Markku Laakso,A D Morris,Palmer Cna.,Palmer Cna.,Igor Rudan,Igor Rudan,Igor Rudan,Eric J.G. Sijbrands,Lincoln D. Stein,Jaakko Tuomilehto,A Uitterlinden,Mark Walker,Richard M. Watanabe,Gonçalo R. Abecasis,Bernhard O. Boehm,Harry Campbell,Mark J. Daly,Mark J. Daly,Mark J. Daly,Andrew T. Hattersley,Oluf Pedersen,Oluf Pedersen,Oluf Pedersen,Inês Barroso,L Groop,Robert Sladek,Unnur Thorsteinsdottir,Unnur Thorsteinsdottir,J.F. Wilson,Thomas Illig,Philippe Froguel,Philippe Froguel,C M van Duijn,Kari Stefansson,David Altshuler,Michael Boehnke,Mark I. McCarthy,Nicole Soranzo,Nicole Soranzo,Eleanor Wheeler,Nicole L. Glazer,Nabila Bouatia-Naji,Reedik Mägi,Joshua C. Randall,Paul Elliott,Paul Elliott,Denis Rybin,Abbas Dehghan,Jouke-Jan Hottenga,Kijoung Song,Anuj Goel,Taina K. Lajunen,Alex S. F. Doney,Christine Cavalcanti-Proença,Meena Kumari,N J Timpson,Carina Zabena,Erik Ingelsson,Erik Ingelsson,Ping An,Jeffrey R. O'Connell,Jian'an Luan,A Elliott,Rosa Maria Roccasecca,François Pattou,Praveen Sethupathy,Yavuz Ariyurek,Philip J. Barter,John Beilby,Yoav Ben-Shlomo,Sven Bergmann,Sven Bergmann,Murielle Bochud,Amélie Bonnefond,Knut Borch-Johnsen,Knut Borch-Johnsen,Yvonne Böttcher,Eric J. Brunner,S J Bumpstead,Chen Y-Di.,P Chines,Robert Clarke,Coin Ljm.,Mark E. Cooper,Laura Crisponi,Day Inm.,de Geus Ejc.,Jérôme Delplanque,A C Fedson,Antje Fischer-Rosinsky,Nita G. Forouhi,MariaGrazia Franzosi,Pilar Galan,Mark O. Goodarzi,J. Graessler,Scott M. Grundy,R. Gwilliam,Göran Hallmans,Naomi Hammond,Xijing Han,Hartikainen A-L.,Caroline Hayward,S C Heath,Serge Hercberg,David R. Hillman,Aroon D. Hingorani,Jennie Hui,Joseph Hung,Joseph Hung,Marika Kaakinen,Jaakko Kaprio,Jaakko Kaprio,Y A Kesaniemi,Mika Kivimäki,Beatrice Knight,Seppo Koskinen,Peter Kovacs,K O Kyvik,G M Lathrop,Debbie A Lawlor,O Le Bacquer,Cécile Lecoeur,Yun Li,Robert W. Mahley,Massimo Mangino,María Teresa Martínez-Larrad,Jarred B. McAteer,Jarred B. McAteer,Ruth McPherson,Christa Meisinger,David Melzer,David Meyre,Braxton D. Mitchell,Sutapa Mukherjee,Silvia Naitza,Matt Neville,Marco Orrù,Ruth E. Pakyz,Giuseppe Paolisso,Cristian Pattaro,Daniel S. Pearson,J F Peden,Nancy L. Pedersen,Pfeiffer Afh.,Irene Pichler,Ozren Polasek,Danielle Posthuma,Simon C. Potter,A Pouta,M. A. Province,Kenneth Rice,Samuli Ripatti,Samuli Ripatti,Fernando Rivadeneira,Olov Rolandsson,A. Sandbaek,M Sandhu,Serena Sanna,Avan Aihie Sayer,Paul Scheet,Udo Seedorf,Stephen J. Sharp,B Shields,Gunnar Sigurðsson,Sijbrands Ejg.,Sijbrands Ejg.,Angela Silveira,Laila Simpson,Andrew B. Singleton,Nicholas L. Smith,Nicholas L. Smith,Ulla Sovio,A Swift,Holly E. Syddall,Syvänen A-C.,Anke Tönjes,A G Uitterlinden,K W van Dijk,K W van Dijk,Dhiraj Varma,Sophie Visvikis-Siest,Veronique Vitart,N Vogelzangs,N Vogelzangs,Gerard Waeber,P J Wagner,P J Wagner,P J Wagner,Andrew Walley,Kim L. Ward,Hugh Watkins,Sarah H. Wild,Gonneke Willemsen,Witteman Jcm.,Yarnell Jwg.,Diana Zelenika,Björn Zethelius,Björn Zethelius,Guangju Zhai,Jing Hua Zhao,M C Zillikens,M C Zillikens,Ingrid B. Borecki,Pierre Meneton,Magnusson Pke.,David M. Nathan,Gordon H. Williams,Kaisa Silander,Kaisa Silander,Stefan R. Bornstein,Peter Schwarz,Jochen Spranger,Fredrik Karpe,Alan R. Shuldiner,Cyrus Cooper,Manuel Serrano-Ríos,Lars Lind,Lyle J. Palmer,Lyle J. Palmer,Paul W. Franks,Shah Ebrahim,Michael Marmot,Alan F. Wright,Michael Stumvoll,Anders Hamsten,Anders Hamsten,Thomas A. Buchanan,Timo T. Valle,Jerome I. Rotter,Penninx Bwjh.,Penninx Bwjh.,Dorret I. Boomsma,Dorret I. Boomsma,Anyuan Cao,Angelo Scuteri,Angelo Scuteri,David Schlessinger,Manuela Uda,Aimo Ruokonen,Jarvelin M-R.,Leena Peltonen,V Mooser,Kiran Musunuru,Kiran Musunuru,Albert V. Smith,Andrew C. Edmondson,Ioannis M. Stylianou,Masahiro Koseki,James P. Pirruccello,James P. Pirruccello,James P. Pirruccello,Daniel I. Chasman,Christopher T. Johansen,Sigrid W. Fouchier,Gina M. Peloso,Gina M. Peloso,Maja Barbalić,Sally L. Ricketts,J. C. Bis,Mary F. Feitosa,Marju Orho-Melander,Olle Melander,Xiaohui Li,Yoon Shin Cho,Min Jin Go,Young-Jin Kim,Lee J-Y.,Taesung Park,K Kim,Xueling Sim,Ong Rt-H.,Damien C. Croteau-Chonka,Leslie A. Lange,Josh Smith,Andreas Ziegler,Weihua Zhang,Zee Ryl.,John Whitfield,John R. Thompson,Ida Surakka,Ida Surakka,J.H. Smit,Juha Sinisalo,Jan Scott,Juha Saharinen,Chiara Sabatti,Lynda M. Rose,Robert Roberts,Mark J. Rieder,Alex N. Parker,Guillaume Paré,Christopher J. O'Donnell,Christopher J. O'Donnell,Markku S. Nieminen,Deborah A. Nickerson,Grant W. Montgomery,Wendy L. McArdle,David Masson,Nicholas G. Martin,Fabio Marroni,Gavin Lucas,Robert Luben,Lokki M-L.,Guillaume Lettre,Lenore J. Launer,Edward G. Lakatta,Reijo Laaksonen,Inke R. König,Khaw K-T.,Lee M. Kaplan,Åsa Johansson,Janssens Acjw.,Wilmar Igl,G K Hovingh,Christian Hengstenberg,Aki S. Havulinna,Aki S. Havulinna,Nicholas D. Hastie,T B Harris,Talin Haritunians,Alyson Hall,L C Groop,Elena Gonzalez,Nelson B. Freimer,Jeanette Erdmann,Kenechi Ejebe,Angela Döring,Anna F. Dominiczak,Serkalem Demissie,Serkalem Demissie,U de Faire,Mark J. Caulfield,S.M. Boekholdt,Themistocles L. Assimes,Thomas Quertermous,Mark Seielstad,Tien Yin Wong,Tai E-S.,Alan B. Feranil,Christopher W. Kuzawa,Herman A. Taylor,S. Gabriel,Hilma Holm,Vilmundur Gudnason,Ronald M. Krauss,Jose M. Ordovas,Jose M. Ordovas,Patricia B. Munroe,J S Kooner,Alan R. Tall,Robert A. Hegele,Kastelein Jjp.,Eric E. Schadt,David P. Strachan,Muredach P. Reilly,Nilesh J. Samani,Heribert Schunkert,L A Cupples,M S Sandhu,Paul M. Ridker,Daniel J. Rader,Sekar Kathiresan +618 more
TL;DR: A meta-analysis of genome-wide association studies in 39,883 individuals of European ancestry to identify genes associated with metabolic disease identifies novel genetic determinants of adiponectin levels, which, taken together, influence risk of T2D and markers of insulin resistance.