G
Gholamreza Tavoosidana
Researcher at Tehran University of Medical Sciences
Publications - 57
Citations - 2882
Gholamreza Tavoosidana is an academic researcher from Tehran University of Medical Sciences. The author has contributed to research in topics: Medicine & Stem cell. The author has an hindex of 16, co-authored 48 publications receiving 2503 citations. Previous affiliations of Gholamreza Tavoosidana include Science for Life Laboratory & Uppsala University.
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Circular chromosome conformation capture (4C) uncovers extensive networks of epigenetically regulated intra-and interchromosomal interactions
Zhihu Zhao,Gholamreza Tavoosidana,Mikael Sjölinder,Anita Göndör,Piero Mariano,Sha Wang,Chandrasekhar Kanduri,Magda Lezcano,Kuljeet Singh Sandhu,Umashankar Singh,Vinod Pant,Vijay K. Tiwari,Sreenivasulu Kurukuti,Rolf Ohlsson +13 more
TL;DR: It is found that the direct interaction between differentially methylated regions was linked to epigenetic regulation of transcription in trans and the patterns of interactions specific to the maternal H19 imprinting control region underwent reprogramming during in vitro maturation of embryonic stem cells.
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CTCF binding at the H19 imprinting control region mediates maternally inherited higher-order chromatin conformation to restrict enhancer access to Igf2
Sreenivasulu Kurukuti,Vijay K. Tiwari,Gholamreza Tavoosidana,Elena M. Pugacheva,Adele Murrell,Zhihu Zhao,Victor V. Lobanenkov,Wolf Reik,Rolf Ohlsson +8 more
TL;DR: Systematic chromosome conformation capture analysis of an imprinting cluster reveals that CTCF has a critical role in the epigenetic regulation of higher-order chromatin structure and gene silencing over considerable distances in the genome.
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Poly(ADP-ribosyl)ation regulates CTCF-dependent chromatin insulation
Wenqiang Yu,Vasudeva Ginjala,Vinod Pant,Igor Chernukhin,Joanne Whitehead,Dawn Farrar,Gholamreza Tavoosidana,Rituparna Mukhopadhyay,Chandrasekhar Kanduri,Mitsuo Oshimura,Andrew P. Feinberg,Victor V. Lobanenkov,Elena Klenova,Rolf Ohlsson +13 more
TL;DR: It is suggested that poly(ADP-ribosyl)ation imparts chromatin insulator properties to CTCF at both imprinted and nonimprinted loci, which has implications for the regulation of expression domains and their demise in pathological lesions.
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Multiple recognition assay reveals prostasomes as promising plasma biomarkers for prostate cancer
Gholamreza Tavoosidana,Gunnar Ronquist,Spyros Darmanis,Junhong Yan,Lena Carlsson,Di Wu,Tim Conze,Pia Ek,Axel Semjonow,Elke Eltze,Anders Larsson,Ulf Landegren,Masood Kamali-Moghaddam +12 more
TL;DR: An extremely sensitive and specific assay for detection of complex target structures such as microvesicles in which the target is first captured via an immobilized antibody and subsequently detected by using four other antibodies with attached DNA strands is developed.
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Exosome loaded alginate hydrogel promotes tissue regeneration in full-thickness skin wounds: An in vivo study
Shilan Shafei,Mehdi Khanmohammadi,Reza Heidari,Hossein Ghanbari,Vajihe Taghdiri Nooshabadi,Saeed Farzamfar,Mostafa Akbariqomi,Nafiseh Sadat Sanikhani,Moloud Absalan,Gholamreza Tavoosidana +9 more
TL;DR: This bioactive wound dressing technique has significantly improved wound closure, collagen synthesis, and vessel formation in the wound area through the application of the composite structure of EXO encapsulated in alginate hydrogel.