G
Gideon Dreyfuss
Researcher at University of Pennsylvania
Publications - 214
Citations - 51297
Gideon Dreyfuss is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Ribonucleoprotein & snRNP. The author has an hindex of 111, co-authored 214 publications receiving 45027 citations. Previous affiliations of Gideon Dreyfuss include National Institutes of Health & Massachusetts Institute of Technology.
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Journal ArticleDOI
U1 snRNP regulates cancer cell migration and invasion in vitro
Jung-Min Oh,Christopher C. Venters,Chao Di,Anna Maria Pinto,Lili Wan,Ihab Younis,Zhiqiang Cai,Chie Arai,Byung Ran So,Jingqi Duan,Gideon Dreyfuss +10 more
TL;DR: An unexpected role for U1 homeostasis (available U1 relative to transcription) in oncogenic and activated cell states is revealed, and U1 is suggested as a potential target for their modulation.
Journal ArticleDOI
Conserved structures and diversity of functions of RNA-binding proteins.
TL;DR: The major RNA-binding motifs are described and examples of how they may function are given.
Journal ArticleDOI
A uniform system for microRNA annotation
Victor R. Ambros,Bonnie Bartel,David P. Bartel,Christopher B. Burge,James C. Carrington,Xuemei Chen,Gideon Dreyfuss,Sean R. Eddy,Sam Griffiths-Jones,Mhairi Marshall,Marjori Matzke,Gary Ruvkun,Thomas Tuschl +12 more
TL;DR: Guidelines are presented for the identification and annotation of new miRNAs from diverse organisms, particularly so that mi RNAs can be reliably distinguished from other RNAs such as small interfering RNAs.
Posted ContentDOI
U1 snRNP regulates cancer cell migration and invasion
Jung-Min Oh,Christopher C. Venters,Chao Di,Anna Maria Pinto,Lili Wan,Ihab Younis,Zhiqiang Cai,Chie Arai,Byung Ran So,Gideon Dreyfuss +9 more
TL;DR: It is shown that U1 AMO also modulates cancer cells’ phenotype, dose-dependently increasing migration and invasion in vitro by up to 500%, whereas U1 over-expression has the opposite effect.
Journal ArticleDOI
hnRNP Proteins and the Biogenesis of mRNA
TL;DR: The hnRNP Proteins Definition and Experimental Criteria and Posttranslational Modifications are described.