Gideon Koren

TL;DR: The results show that the model, which assumes a functionally single drug efflux pump in the apical membrane with diffusion across two membranes and intercellular junctions, is the least complex model with which to quantitatively reproduce the characteristics of the data.

TL;DR: This work introduces a novel technique to quantify FAEEs in meconium using headspace-solid-phase microextraction (HS-SPME) coupled with gas chromatography-mass spectrometry (GC-MS), which improves on previous approaches by decreasing sample preparation time, eliminating the need for organic solvents, and reducing the required sample size.

TL;DR: The findings do not support an association between exposure to WTN up to 46 dBA and elevated self-reported and objectively defined measures of stress.

TL;DR: An understanding of this genotype-phenotype relationship will allow for prediction of susceptible or favorable genotypes in order to personalize medication choices to minimize fetal exposure to teratogens, or to maximize pharmacological therapy to the fetus.

TL;DR: The use of SGA during the first trimester of pregnancy was associated with a significant increased risk for major congenital malformations, but the absence of a specific pattern of malforms makes it difficult to identify an explicit risk posed by SGAs, and therefore, further studies sufficiently controlling for confounding factors are needed.