G
Gideon Rechavi
Researcher at Sheba Medical Center
Publications - 461
Citations - 35249
Gideon Rechavi is an academic researcher from Sheba Medical Center. The author has contributed to research in topics: Gene & RNA editing. The author has an hindex of 88, co-authored 454 publications receiving 30751 citations. Previous affiliations of Gideon Rechavi include Harvard University & Tel Aviv University.
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Journal ArticleDOI
Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq
Dan Dominissini,Sharon Moshitch-Moshkovitz,Schraga Schwartz,Schraga Schwartz,Mali Salmon-Divon,Lior Ungar,Sivan Osenberg,Sivan Osenberg,Karen Cesarkas,Jasmine Jacob-Hirsch,Ninette Amariglio,Martin Kupiec,Rotem Sorek,Gideon Rechavi,Gideon Rechavi +14 more
TL;DR: The findings suggest that RNA decoration by m6A has a fundamental role in regulation of gene expression, and a subset of stimulus-dependent, dynamically modulated sites is identified.
Journal ArticleDOI
Gene expression regulation mediated through reversible m 6 A RNA methylation
TL;DR: This Review focuses on reversible methylation through the most prevalent mammalian mRNA internal modification, N6-methyladenosine (m6A), and indicates dynamic regulatory roles that are analogous to the well-known reversible epigenetic modifications of DNA and histone proteins.
Journal ArticleDOI
m6A mRNA methylation facilitates resolution of naïve pluripotency toward differentiation
Shay Geula,Sharon Moshitch-Moshkovitz,Dan Dominissini,Abed AlFatah Mansour,Nitzan Kol,Mali Salmon-Divon,Vera Hershkovitz,Eyal Peer,Nofar Mor,Yair S. Manor,Moshe Shay Ben-Haim,Eran Eyal,Sharon Yunger,Yishay Pinto,Diego Jaitin,Sergey Viukov,Yoach Rais,Vladislav Krupalnik,Elad Chomsky,Mirie Zerbib,Itay Maza,Yoav Rechavi,Rada Massarwa,Suhair Hanna,Suhair Hanna,Ido Amit,Erez Y. Levanon,Ninette Amariglio,Ninette Amariglio,Noam Stern-Ginossar,Noa Novershtern,Gideon Rechavi,Jacob H. Hanna +32 more
TL;DR: It is shown that N6-methyladenosine (m6A), a messenger RNA (mRNA) modification present on transcripts of pluripotency factors, drives this transition from the pluripotent to the differentiated state.
Journal ArticleDOI
Donor-Derived Brain Tumor Following Neural Stem Cell Transplantation in an Ataxia Telangiectasia Patient
Ninette Amariglio,Abraham Hirshberg,Bernd W. Scheithauer,Yoram Cohen,Ron Loewenthal,Luba Trakhtenbrot,Nurit Paz,Maya Koren-Michowitz,Dalia Waldman,Leonor Leider-Trejo,Amos Toren,Shlomi Constantini,Gideon Rechavi +12 more
TL;DR: The findings here suggest that neuronal stem/progenitor cells may be involved in gliomagenesis and provide the first example of a donor-derived brain tumor complicating neural stem cell therapy.
Journal ArticleDOI
Systematic identification of abundant A-to-I editing sites in the human transcriptome
Erez Y. Levanon,Erez Y. Levanon,Eli Eisenberg,Rodrigo Yelin,Sergey Nemzer,Martina Hallegger,Ronen Shemesh,Zipora Y. Fligelman,Avi Shoshan,Sarah Pollock,Dan Sztybel,Moshe Olshansky,Gideon Rechavi,Michael F. Jantsch +13 more
TL;DR: A computational search for ADAR editing sites in the human transcriptome is described, using millions of available expressed sequences and indicates the role of editing in controlling dsRNA stability.