G
Gilbert Gosselin
Researcher at Montreal Heart Institute
Publications - 71
Citations - 9759
Gilbert Gosselin is an academic researcher from Montreal Heart Institute. The author has contributed to research in topics: Percutaneous coronary intervention & Myocardial infarction. The author has an hindex of 26, co-authored 68 publications receiving 8283 citations. Previous affiliations of Gilbert Gosselin include New York University & St. Michael's Hospital.
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Journal ArticleDOI
Optimal Medical Therapy with or without PCI for Stable Coronary Disease
William E. Boden,Koon K. Teo,Pamela M. Hartigan,David J. Maron,William J. Kostuk,Merril L. Knudtson,Marcin Dada,Paul Casperson,Crystal L. Harris,Bernard R. Chaitman,Leslee J. Shaw,Gilbert Gosselin,Shah Nawaz,Lawrence M. Title,Gerald T. Gau,Alvin Blaustein,David C. Booth,Eric R. Bates,John A. Spertus,Daniel S. Berman,William S. Weintraub +20 more
TL;DR: As an initial management strategy in patients with stable coronary artery disease, PCI did not reduce the risk of death, myocardial infarction, or other major cardiovascular events when added to optimal medical therapy.
Journal ArticleDOI
Optimal Medical Therapy With or Without Percutaneous Coronary Intervention to Reduce Ischemic Burden Results From the Clinical Outcomes Utilizing Revascularization and Aggressive Drug Evaluation (COURAGE) Trial Nuclear Substudy
Leslee J. Shaw,Daniel S. Berman,David J. Maron,G.B. John Mancini,Sean W. Hayes,Pamela M. Hartigan,William S. Weintraub,Robert A. O'Rourke,Marcin Dada,John A. Spertus,Bernard R. Chaitman,John D. Friedman,Piotr J. Slomka,Gary V. Heller,Guido Germano,Gilbert Gosselin,Peter B. Berger,William J. Kostuk,Ronald G. Schwartz,Merill L Knudtson,Emir Veledar,Eric R. Bates,Benjamin D. McCallister,Koon K. Teo,William E. Boden +24 more
TL;DR: In COURAGE patients who underwent serial MPS, adding PCI to OMT resulted in greater reduction in ischemia compared with OMT alone, and the findings suggest a treatment target of ≥5% ischemic myocardium reduction with O MT with or without coronary revascularization.
Journal ArticleDOI
Initial invasive or conservative strategy for stable coronary disease.
David J. Maron,Judith S. Hochman,Harmony R. Reynolds,Sripal Bangalore,Sean M. O'Brien,William E. Boden,Bernard R. Chaitman,Roxy Senior,Roxy Senior,Jose Lopez-Sendon,Karen P. Alexander,Renato D. Lopes,Leslee J. Shaw,Jeffrey S. Berger,Jonathan D. Newman,Mandeep S. Sidhu,Shaun G. Goodman,Witold Rużyłło,Gilbert Gosselin,Aldo P. Maggioni,Harvey D. White,Balram Bhargava,James K. Min,G.B. John Mancini,Daniel S. Berman,Michael H. Picard,Raymond Y. Kwong,Ziad A. Ali,Ziad A. Ali,Daniel B. Mark,John A. Spertus,Mangalath Narayanan Krishnan,Ahmed Elghamaz,Nagaraja Moorthy,Whady Hueb,Marcin Demkow,Kreton Mavromatis,Kreton Mavromatis,Olga L. Bockeria,Jesús Peteiro,Todd D. Miller,Hanna Szwed,Rolf Doerr,Matyas Keltai,Joseph B. Selvanayagam,P. Gabriel Steg,Claes Held,Claes Held,Shun Kohsaka,Stavroula Mavromichalis,Ruth Kirby,Neal Jeffries,Frank E. Harrell,Frank W. Rockhold,Samuel Broderick,T. Bruce Ferguson,David O. Williams,Robert A. Harrington,Gregg W. Stone,Yves Rosenberg +59 more
TL;DR: Evidence that an initial invasive strategy, as compared with an initial conservative strategy, reduced the risk of ischemic cardiovascular events or death from any cause over a median of 3.2 years is not found.
Journal ArticleDOI
Oral anticoagulant and antiplatelet therapy and peripheral arterial disease.
Sonia S. Anand,Sonia S. Anand,Salim Yusuf,Changchun Xie,Janice Pogue,John W. Eikelboom,Andrzej Budaj,Bruce Sussex,Lisheng Liu,Randy Guzman,Claudio S. Cinà,Richard Crowell,Matyas Keltai,Gilbert Gosselin +13 more
TL;DR: In patients with peripheral arterial disease, the combination of an oral anticoagulant and antiplatelet therapy was not more effective than anti platelet therapy alone in preventing major cardiovascular complications and was associated with an increase in life-threatening bleeding.
Journal ArticleDOI
Human Pulmonary Circulation Is an Important Site for Both Clearance and Production of Endothelin-1
TL;DR: The human lung is an important site for both clearance and production of ET-1 and reduced pulmonary clearance or increased production of this peptide may contribute to the increase in circulating levels found in various cardiovascular conditions.