G
Giorgio Olivetti
Researcher at University of Parma
Publications - 112
Citations - 13979
Giorgio Olivetti is an academic researcher from University of Parma. The author has contributed to research in topics: Ventricle & Myocyte. The author has an hindex of 54, co-authored 111 publications receiving 13666 citations. Previous affiliations of Giorgio Olivetti include New York Medical College & Cardiovascular Institute of the South.
Papers
More filters
Journal ArticleDOI
Apoptosis in the Failing Human Heart
Giorgio Olivetti,R Abbi,Federico Quaini,Jan Kajstura,Cheng W,James A. Nitahara,Eugenio Quaini,C. Di Loreto,Carlo Alberto Beltrami,Stanislaw Krajewski,John C. Reed,Piero Anversa +11 more
TL;DR: Programmed death of myocytes occurs in the decompensated human heart in spite of the enhanced expression of BCL2; this phenomenon may contribute to the progression of cardiac dysfunction.
Journal Article
Apoptotic and necrotic myocyte cell deaths are independent contributing variables of infarct size in rats.
Jan Kajstura,Wei Cheng,Krzysztof Reiss,William A. Clark,Edmund H. Sonnenblick,Stanislaw Krajewski,John C. Reed,Giorgio Olivetti,Piero Anversa +8 more
TL;DR: Programmed myocyte cell death is the major form of myocardial damage produced by occlusion of a major epicardial coronary artery, whereas necrotic myocytes cell death follows apoptosis and contributes to the progressive loss of cells with time after infarction.
Journal ArticleDOI
Cardiomyopathy of the aging human heart. Myocyte loss and reactive cellular hypertrophy.
TL;DR: Regression analysis demonstrated that the aging process was characterized by a loss of 38 million and 14 million myocyte nuclei/yr in the left and right ventricular myocardium, respectively, which may represent the structural basis for the reduced compensatory capacity of the aged heart.
Journal ArticleDOI
Stretch-induced programmed myocyte cell death.
Wei Cheng,Baosheng Li,Jan Kajstura,Peng Li,Michael S. Wolin,Edmund H. Sonnenblick,Thomas H. Hintze,Giorgio Olivetti,Piero Anversa +8 more
TL;DR: Overstretching appears to be coupled with oxidant stress, expression of Fas, programmed cell death, architectural rearrangement of myocytes, and impairment in force development of the myocardium.
Journal ArticleDOI
Gender differences and aging: effects on the human heart.
Giorgio Olivetti,Giovanna Giordano,Giovanna Giordano,Domenico Corradi,Domenico Corradi,M Melissari,M Melissari,C. Lagrasta,C. Lagrasta,Steven R. Gambert,Piero Anversa +10 more
TL;DR: Investigating the changes in myocyte size and number in the left and right ventricles that occur with aging in the female and male heart concluded that gender differences may play a significant role in the detrimental effects of the aging process on the heart.