Giovanni Giugliano

TL;DR: After 2 years of follow-up, patients following the Mediterranean-style diet consumed more foods rich in monounsaturated fat, polyunsaturatedfat, and fiber and had a lower ratio of omega-6 to omega-3 fatty acids.

TL;DR: Hyperglycemia acutely increases circulating cytokine concentrations by an oxidative mechanism, and this effect is more pronounced in subjects with IGT, which suggests a causal role for hyper glycemia in the immune activation of diabetes.

TL;DR: A multidisciplinary program aimed to reduce body weight in obese women through lifestyle changes was associated with a reduction in markers of vascular inflammation and insulin resistance.

TL;DR: A randomized, single-blind trial conducted from June 2001 to January 2004 at a university hospital in Italy among 180 patients with the metabolic syndrome, as defined by the Adult Treatment Panel III, was conducted to assess the effect of a Mediterranean-style diet on endothelial function and vascular inflammatory markers in patients with metabolic syndrome.

TL;DR: In obese women, endothelial activation correlates with visceral body fat, possibly through inappropriate secretion of cytokines, and sustained weight loss represents a safe method for downregulating the inflammatory state and ameliorating endothelial dysfunction in obese women.