G
Gitte M. Knudsen
Researcher at University of Copenhagen
Publications - 558
Citations - 19926
Gitte M. Knudsen is an academic researcher from University of Copenhagen. The author has contributed to research in topics: Serotonergic & Medicine. The author has an hindex of 64, co-authored 506 publications receiving 16852 citations. Previous affiliations of Gitte M. Knudsen include Health Science University & Southern Illinois University Carbondale.
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Journal ArticleDOI
Consensus nomenclature for in vivo imaging of reversibly binding radioligands
Robert B. Innis,Vincent J. Cunningham,Jacques Delforge,Masahiro Fujita,Albert Gjedde,Roger N. Gunn,James E. Holden,Sylvain Houle,Sung-Cheng Huang,Masanori Ichise,Hidehiro Iida,Hiroshi Ito,Yuichi Kimura,Robert A. Koeppe,Gitte M. Knudsen,Juhani Knuuti,Adriaan A. Lammertsma,Marc Laruelle,Jean Logan,Ralph Paul Maguire,Mark A. Mintun,Evan D. Morris,Ramin V. Parsey,Julie C. Price,Mark Slifstein,Vesna Sossi,Tetsuya Suhara,John R. Votaw,Dean F. Wong,Richard E. Carson +29 more
TL;DR: An international group of experts in pharmacokinetic modeling recommends a consensus nomenclature to describe in vivo molecular imaging of reversibly binding radioligands.
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Blood BDNF concentrations reflect brain-tissue BDNF levels across species.
Anders B. Klein,Rebecca Williamson,Martin A. Santini,Christoffer Clemmensen,Anders Ettrup,Maribel Rios,Gitte M. Knudsen,Susana Aznar +7 more
TL;DR: Preliminary data support the view that measures of blood and plasma BDNF levels reflect brain-tissue BDNF Levels, and find a significant positive correlation between frontal cortex and hippocampalBDNF levels in mice.
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MR-based automatic delineation of volumes of interest in human brain PET images using probability maps
Claus Svarer,Karine Madsen,Steen G. Hasselbalch,Lars H. Pinborg,Steven Haugbøl,Vibe G. Frokjaer,Søren Holm,Olaf B. Paulson,Gitte M. Knudsen +8 more
TL;DR: In this article, an observer-independent approach for automatic generation of volume-of-interest (VOI) brain templates to be used in emission tomography studies of the brain was developed and validated.
Journal ArticleDOI
Autoregulation of cerebral blood flow in patients resuscitated from cardiac arrest.
Claus Sundgreen,Fin Stolze Larsen,Tina Maria Herzog,Gitte M. Knudsen,Søren Boesgaard,Jan Aldershvile +5 more
TL;DR: In a majority of patients in the acute phase after cardiac arrest, cerebral autoregulation is either absent or right-shifted, which indicates that MAP should be kept at a higher level than commonly accepted to secure cerebral perfusion.
Journal ArticleDOI
Species differences in blood-brain barrier transport of three positron emission tomography radioligands with emphasis on P-glycoprotein transport.
Stina Syvänen,Örjan Lindhe,Mikael Palner,Birgitte Rahbek Kornum,Obaidur Rahman,Bengt Långström,Gitte M. Knudsen,Margareta Hammarlund-Udenaes +7 more
TL;DR: Differences in plasma protein binding and metabolism did not explain the species-related differences in brain uptake of three radiolabeled P-glycoprotein substrates across species using positron emission tomography, which is important for interpretation of brain drug delivery when extrapolating preclinical data to humans.