G
Giuseppe Luna
Researcher at Curtin University
Publications - 26
Citations - 306
Giuseppe Luna is an academic researcher from Curtin University. The author has contributed to research in topics: Triethyl orthoformate & Bile acid. The author has an hindex of 8, co-authored 23 publications receiving 187 citations. Previous affiliations of Giuseppe Luna include Monash University.
Papers
More filters
Journal ArticleDOI
Inhibitors of Xanthine Oxidase: Scaffold Diversity and Structure-Based Drug Design.
TL;DR: The molecular structures and activities of the multiple classes of inhibitors that have been developed since the discovery of allopurinol are discussed, with a brief review of the molecular interactions between inhibitors and XO active site residues for the most important molecules.
Journal ArticleDOI
A one-pot, three-component aminotriazine annulation onto 5-aminopyrazole-4-carbonitriles under microwave irradiation
TL;DR: In this article, a one-pot, three-component, microwave assisted reaction of 5-aminopyrazole-4-carbonitriles, triethyl orthoformate and cyanamide afforded novel 7-arylamino-substituted 4-amina-addicted 8-carbonite.
Journal ArticleDOI
A one-pot, three-component, microwave-assisted synthesis of novel 7-amino-substituted 4-aminopyrazolo[1,5-a][1,3,5]triazine-8-carbonitriles
TL;DR: In this article, a three-component reaction of 3-amino-substituted 5-aminopyrazole-4-carbonitriles, cyanamide and triethyl orthoformate under microwave irradiation was used for the synthesis of pyrazolo.
Journal ArticleDOI
A new, one-pot, multicomponent synthesis of 5-aza-9-deaza-adenines under microwave irradiation ☆
TL;DR: In this article, a three-component method for the synthesis of 5-aza-9-deaza-adenines was developed, where Aminopyrazoles react in a one-pot fashion with triethyl orthoformate and cyanamide under microwave irradiation.
Journal ArticleDOI
Design, synthesis, and biological evaluation of novel arylcarboxamide derivatives as anti-tubercular agents
Shahinda S.R. Alsayed,Shichun Lun,Giuseppe Luna,Chau Chun Beh,Alan D. Payne,Neil R. Foster,William R. Bishai,William R. Bishai,Hendra Gunosewoyo +8 more
TL;DR: Several arylcarboxamides were rationally designed based on the previously reported homology model and the recently published crystal structure of the mycobacterial membrane protein large 3 (MmpL3) and studied for their drug-likeness using Lipinski's rule of five.