Giuseppe Mancia

TL;DR: The paper will finally review the pharmacological and non-pharmacological interventions acting on the sympathetic drive and emphasis will be given to the new approaches, such as renal nerves ablation and carotid baroreceptor stimulation, which have been shown to exert sympathoinhibitory effects.

TL;DR: Administration of acetazolamide may antagonize the reduction in subendocardial oxygen supply triggered by exposure to hypobaric hypoxia and endanger myocardial viability under high-altitude exposure, according to this parameter.

TL;DR: It was shown in the SAMPLE study that T/P is not correlated to changes in left ventricular mass induced by treatment, and thus has a limited clinical value.

TL;DR: Evidence is provided that a high prevalence of hyperuricemia occurs in hypertensive patients from central and east Europe and that gender-related differences in the association between SUA and cardionephrometabolic variables exist.

TL;DR: In this article, the authors support the view that white-coat hypertension (WCH) is not an innocent condition but a condition associated with an increased cardiovascular risk, based on the evidence that compared with normotensive controls, subjects with WCH have an increased prevalence of metabolic risk factors and asymptomatic organ damage, more frequently progress to high cardiovascular risk states such as sustained hypertension, diabetes mellitus, and left ventricular hypertrophy.