Giuseppe Mancia

TL;DR: Despite unmet goals, antihypertensive treatment has provided throughout the years successful results and future efforts will be need to achieve a better BP control in the population to obtain a greater CV protection.

TL;DR: The conclusion being that calcium channel blockers may be associated with lower survival, and that diuretics may have disadvantages in patients with left ventricular hypertrophy and smaller left Ventricular cavity dimensions, β-blockers may be well tolerated and a better choice for patients with concomitant coronary artery disease and arrhythmias.

TL;DR: It will be shown that 24 hour blood pressure values correlate more closely than clinic blood pressure with various measures of the end organ damage of hypertension, suggesting that it may reflect better than traditional blood pressure measurements the cardiovascular consequences of this condition.

TL;DR: The currently accepted concept that, to maximize cardiovascular protection, BP control needs to be as much as possible steady over time implies that physicians should not consider absence of BP control at single visits as of marginal clinical importance (and thus indulge in therapeutic inertia) because this may reduce patients’ chance of survival free of diseases.

TL;DR: The data show that in the metabolic syndrome not only peripheral but also cardiac sympathetic drive is markedly potentiated and HR can be regarded as a marker of adrenergic overdrive characterizing this clinical condition.