Giuseppe Mancia

TL;DR: The present meta‐analysis shows that MetS is associated with both ultrasonographic phenotypes of carotid damage, consistent with the view of MetS as a cluster of hemodynamic and nonhemodynamic factors promoting vascular hypertrophy and plaque.

TL;DR: A gene-centric association study of metabolic syndrome in 98 major cardiometabolic genes in the large, well phenotyped Pressioni Arteriose Monitorate e Loro Associazioni (PAMELA) study shows the SNP rs17055869 near the 3′ end of ADRA1A is significantly associated with metabolic syndrome and it may be involved in determining a greater level of sympathetic activation in metabolic syndrome patients.

TL;DR: A BP-independent effect of empagliflozin on cardiovascular and heart failure outcomes is suggested as well of the early drop in SBP on treatment, which was associated with new/worsening nephropathy.

TL;DR: While prospective studies on the prognostic value of ambulatory blood pressure are awaited, use of this approach should be restricted to a limited number of clinical circumstances and used only in specialized centers.

TL;DR: Estimating the cost-effectiveness of enhancing adherence to blood pressure (BP)-lowering drug therapy in a large population without signs of preexisting cardiovascular (CV) disease found it to offer important benefits in reducing the risk of CV outcome, but at a substantial cost.