Giuseppe Mancia

TL;DR: In this paper, the authors pointed out that neural cardiovascular regulation is characterized by a complex interaction between central and reflex mechanisms, with the contribution of other important factors such as respiratory frequency and depth.

TL;DR: In the upcoming ESH/ESC guidelines for the management of arterial hypertension, therapeutic options of treatment resistant hypertension will be addressed, but only briefly, and thus it is the focus of this paper to provide detailed and updated information on this innovative interventional technique.

TL;DR: The rationale, design and first baseline data from the Global SYMPLICITY registry are presented, and a benefit from renal denervation in a variety of conditions such as chronic kidney disease, glucose intolerance, sleep apnoea and heart failure are suggested.

TL;DR: In this paper, a study was designed to assess whether a diuretic- or an angiotensin-converting enzyme inhibitor-based treatment can reduce arterial wall hypertrophy of a distal muscular medium-sized artery and the stiffness of a proximal large elastic artery.

TL;DR: Results from the SAMPLE trial show the superiority of mean 24-h, daytime and night-time blood pressures over clinic readings in predicting the regression of left ventricular mass index in treated hypertensive patients and a direct, positive relationship has been established between 24-H blood pressure variability and the severity and rate of progression of end-organ damage.